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本文引用的文献

1
Presence of SXT integrating conjugative element in marine bacteria isolated from the mucus of the coral Fungia echinata from Andaman Sea.从安达曼海的珊瑚 Fungia echinata 的黏液中分离出的海洋细菌中存在 SXT 整合共轭元件。
FEMS Microbiol Lett. 2013 Jan;338(2):118-23. doi: 10.1111/1574-6968.12033. Epub 2012 Nov 16.
2
Genomic diversity of 2010 Haitian cholera outbreak strains.2010 年海地霍乱疫情菌株的基因组多样性。
Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):E2010-7. doi: 10.1073/pnas.1207359109. Epub 2012 Jun 18.
3
Genomic analysis of ICEVchBan8: An atypical genetic element in Vibrio cholerae.肠聚集性大肠埃希菌噬菌体 VchBan8 的基因组分析：一种霍乱弧菌中的非典型遗传元件。
FEBS Lett. 2012 Jun 4;586(11):1617-21. doi: 10.1016/j.febslet.2012.03.064. Epub 2012 Apr 18.
4
Integrating conjugative elements as vectors of antibiotic, mercury, and quaternary ammonium compound resistance in marine aquaculture environments.在海洋水产养殖环境中，整合转座子作为抗生素、汞和季铵化合物抗性的载体。
Antimicrob Agents Chemother. 2012 May;56(5):2619-26. doi: 10.1128/AAC.05997-11. Epub 2012 Feb 6.
5
Drug-resistance mechanisms in Vibrio cholerae O1 outbreak strain, Haiti, 2010.霍乱弧菌 O1 暴发菌株的耐药机制，海地，2010 年。
Emerg Infect Dis. 2011 Nov;17(11):2151-4. doi: 10.3201/eid1711.110720.
6
Evidence for several waves of global transmission in the seventh cholera pandemic.第七次霍乱大流行中存在多次全球传播波次的证据。
Nature. 2011 Aug 24;477(7365):462-5. doi: 10.1038/nature10392.
7
New V. cholerae atypical El Tor variant emerged during the 2006 epidemic outbreak in Angola.2006 年安哥拉疫情期间出现了新型霍乱弧菌非典型埃尔托变体。
BMC Microbiol. 2011 Jun 13;11:130. doi: 10.1186/1471-2180-11-130.
8
Origin of Vibrio cholerae in Haiti.海地霍乱弧菌的起源
Lancet Infect Dis. 2011 Apr;11(4):262. doi: 10.1016/S1473-3099(11)70078-0.
9
ICEVchInd5 is prevalent in epidemic Vibrio cholerae O1 El Tor strains isolated in India.ICEVchInd5 在印度流行的埃尔托弧菌 O1 霍乱菌株中普遍存在。
Int J Med Microbiol. 2011 Apr;301(4):318-24. doi: 10.1016/j.ijmm.2010.11.005. Epub 2011 Jan 26.
10
Comparative ICE genomics: insights into the evolution of the SXT/R391 family of ICEs.比较 ICE 基因组学：对 SXT/R391 家族 ICEs 进化的深入了解。
PLoS Genet. 2009 Dec;5(12):e1000786. doi: 10.1371/journal.pgen.1000786. Epub 2009 Dec 24.

在海地的霍乱弧菌非 O1/非 O139 分离株中检测到一种新的整合接合元件。

A new integrative conjugative element detected in Haitian isolates of Vibrio cholerae non-O1/non-O139.

机构信息

Maryland Pathogen Research Institute, University of Maryland, College Park, MD 20742, USA.

University College London Genetics Institute, University College London, London WC1E 6BT, UK.

出版信息

Res Microbiol. 2013 Nov;164(9):891-893. doi: 10.1016/j.resmic.2013.08.004. Epub 2013 Aug 28.

DOI:10.1016/j.resmic.2013.08.004
PMID:23994142
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3999591/
Abstract

The presence of SXT/R391-related integrating conjugative elements (ICEs) in Vibrio cholerae O1 and non-O1/non-O139 isolated from clinical and environmental samples in Haiti in 2010 was studied. The main finding of this work was the identification of the novel ICEVchHai2 among closely related V. cholerae non-O1/non-O139 clinical strains. The mosaic structure of this element confirms the role of ICEs as efficient recombination systems whereby new genetic material can be acquired and exchanged, according V. cholerae strains new accessory functions.

摘要

本研究调查了 2010 年海地临床和环境样本中分离的霍乱弧菌 O1 和非 O1/O139 菌株中 SXT/R391 相关整合接合元件（ICEs）的存在情况。本工作的主要发现是在密切相关的非 O1/O139 霍乱弧菌临床株中鉴定出新型 ICEVchHai2。该元件的镶嵌结构证实了 ICEs 作为有效的重组系统的作用，通过该系统可以获得和交换新的遗传物质，从而赋予霍乱弧菌菌株新的附加功能。