在海地的霍乱弧菌非 O1/非 O139 分离株中检测到一种新的整合接合元件。
A new integrative conjugative element detected in Haitian isolates of Vibrio cholerae non-O1/non-O139.
机构信息
Maryland Pathogen Research Institute, University of Maryland, College Park, MD 20742, USA.
University College London Genetics Institute, University College London, London WC1E 6BT, UK.
出版信息
Res Microbiol. 2013 Nov;164(9):891-893. doi: 10.1016/j.resmic.2013.08.004. Epub 2013 Aug 28.
Abstract
The presence of SXT/R391-related integrating conjugative elements (ICEs) in Vibrio cholerae O1 and non-O1/non-O139 isolated from clinical and environmental samples in Haiti in 2010 was studied. The main finding of this work was the identification of the novel ICEVchHai2 among closely related V. cholerae non-O1/non-O139 clinical strains. The mosaic structure of this element confirms the role of ICEs as efficient recombination systems whereby new genetic material can be acquired and exchanged, according V. cholerae strains new accessory functions.
摘要
本研究调查了 2010 年海地临床和环境样本中分离的霍乱弧菌 O1 和非 O1/O139 菌株中 SXT/R391 相关整合接合元件（ICEs）的存在情况。本工作的主要发现是在密切相关的非 O1/O139 霍乱弧菌临床株中鉴定出新型 ICEVchHai2。该元件的镶嵌结构证实了 ICEs 作为有效的重组系统的作用，通过该系统可以获得和交换新的遗传物质，从而赋予霍乱弧菌菌株新的附加功能。
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