Pradeep Balakrishnan, Rai Praveen, Mohan Seethappa A, Shekhar Mudagandur S, Karunasagar Indrani
Krishi Vigyan Kendra, Indian Institute of Spices Research, Peruvannamuzhi, Kozhikode, 673528 Kerala India.
Indian J Virol. 2012 Sep;23(2):161-74. doi: 10.1007/s13337-012-0079-y. Epub 2012 Aug 14.
White spot syndrome virus (WSSV) is the most serious viral pathogen of cultured shrimp. It is a highly virulent virus that can spread quickly and can cause up to 100 % mortality in 3-10 days. WSSV is a large enveloped double stranded DNA virus belonging to genus Whispovirus of the virus family Nimaviridae. It has a wide host range among crustaceans and mainly affects commercially cultivated marine shrimp species. The virus infects all age groups causing large scale mortalities and the foci of infection are tissues of ectodermal and mesodermal origin, such as gills, lymphoid organ and cuticular epithelium. The whole genome sequencing of WSSV from China, Thailand and Taiwan have revealed minor genetic differences among different strains. There are varying reports regarding the factors responsible for WSSV virulence which include the differences in variable number of tandem repeats, the genome size and presence or absence of different proteins. Aim of this review is to give current information on the status, host range, pathogenesis and diagnosis of WSSV infection.
白斑综合征病毒（WSSV）是养殖虾类最严重的病毒病原体。它是一种高致病性病毒，传播迅速，可在3至10天内导致高达100%的死亡率。WSSV是一种大型包膜双链DNA病毒，属于病毒科Nimaviridae的Whispovirus属。它在甲壳类动物中有广泛的宿主范围，主要影响商业养殖的海洋虾类品种。该病毒感染所有年龄组，导致大规模死亡，感染部位是外胚层和中胚层起源的组织，如鳃、淋巴器官和表皮上皮。来自中国、泰国和台湾的WSSV全基因组测序显示不同毒株之间存在微小的遗传差异。关于WSSV毒力的影响因素有不同的报道，包括串联重复可变数目的差异、基因组大小以及不同蛋白质的存在与否。本综述的目的是提供有关WSSV感染的现状、宿主范围、发病机制和诊断的最新信息。
