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孕期血液学参数的生理变化。

Physiological changes in hematological parameters during pregnancy.

作者信息

Chandra Surabhi, Tripathi Anil Kumar, Mishra Sanjay, Amzarul Mohammad, Vaish Arvind Kumar

机构信息

Department of Clinical Hematology and Medical Oncology, CSM Medical University, Lucknow, 226003 UP India.

出版信息

Indian J Hematol Blood Transfus. 2012 Sep;28(3):144-6. doi: 10.1007/s12288-012-0175-6. Epub 2012 Jul 15.

DOI:10.1007/s12288-012-0175-6
PMID:23997449
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3422383/
Abstract

Pregnancy is a state characterized by many physiological hematological changes, which may appear to be pathological in the non-pregnant state. The review highlights most of these changes along with the scientific basis for the same, as per the current knowledge, with a special reference to the red blood and white blood cells, platelets and hemostatic profile.

摘要

怀孕是一种具有许多生理性血液学变化的状态，这些变化在非怀孕状态下可能看似病理性的。根据目前的知识，本综述重点介绍了其中的大多数变化及其科学依据，并特别提及了红细胞、白细胞、血小板和止血情况。

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本文引用的文献

1
Plasma volume expansion in pregnancy: implications for biomarkers in population studies.孕期血浆容量扩充：对人群研究中生物标志物的影响。
Cancer Epidemiol Biomarkers Prev. 2007 Sep;16(9):1720-3. doi: 10.1158/1055-9965.EPI-07-0311.
2
Platelet activation in pregnancy-induced hypertension.妊娠期高血压疾病中的血小板活化
Thromb Res. 2005;116(5):377-83. doi: 10.1016/j.thromres.2005.01.009. Epub 2005 Feb 24.
3
D-dimer concentrations in normal pregnancy: new diagnostic thresholds are needed.正常妊娠中的D-二聚体浓度：需要新的诊断阈值。
Clin Chem. 2005 May;51(5):825-9. doi: 10.1373/clinchem.2004.044883. Epub 2005 Mar 11.
4
D-dimer testing in pregnancy.孕期的D-二聚体检测
Pathophysiol Haemost Thromb. 2003;33(5-6):327-9. doi: 10.1159/000083822.
5
New reference values for routine blood samples and human neutrophilic lipocalin during third-trimester pregnancy.孕晚期常规血液样本及人嗜中性粒细胞脂质运载蛋白的新参考值。
Scand J Clin Lab Invest. 2001;61(8):583-92. doi: 10.1080/003655101753267937.
6
Plasma volume expansion in early pregnancy.妊娠早期的血浆容量扩充
Obstet Gynecol. 2001 May;97(5 Pt 1):669-72. doi: 10.1016/s0029-7844(00)01222-9.
7
Neutrophil function in pregnancy and rheumatoid arthritis.孕期及类风湿关节炎中的中性粒细胞功能
Ann Rheum Dis. 2000 Jul;59(7):555-64. doi: 10.1136/ard.59.7.555.
8
Gestational thrombocytopenia.妊娠期血小板减少症。
Clin Obstet Gynecol. 1999 Jun;42(2):327-34. doi: 10.1097/00003081-199906000-00017.
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Pregnancy-associated thrombocytopenia revisited: assessment and follow-up of 50 cases.再探妊娠相关性血小板减少症：50例病例的评估与随访
Blood. 1998 Dec 15;92(12):4573-80.
10
Activated protein C sensitivity, protein C, protein S and coagulation in normal pregnancy.正常妊娠时活化蛋白C敏感性、蛋白C、蛋白S与凝血情况
Thromb Haemost. 1998 Jun;79(6):1166-70.