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低密度微丝蚴血症作为一例性质可疑的不明原因腹水的致病因素。

Low density microfilaraemia as a causative agent in a case of unexplained ascitis of suspicious nature.

作者信息

Mannan Rahul, Bhasin Tejinder Singh, Manjari Mridu, Misra Vatsala

机构信息

Associate Professor, Department of Pathology, Sri Guru Ram Das Institute of Medical Sciences and Research , Amritsar - 143001, Punjab, India .

出版信息

J Clin Diagn Res. 2013 Jul;7(7):1441-3. doi: 10.7860/JCDR/2013/5467.3162. Epub 2013 Jul 1.

Abstract

It is estimated that 120 million people worldwide are affected by filariasis. In the South East and South Asian region, Wuchereria bancrofti is the most prevalent parasite causing filariais in 99.4 % of cases. In the present case the parasite was a cause of unexplained ascitis in a young female whose previous cytological report was suspicious in nature. Extensive physical and radiological assesment was not able to determine the cause of ascitis. Repeat cytological examinantion revealed a few microfilariae of Wuchereria bancrofti. The patient was diagnosed as a case of low density microfilaremia and was put on anti-filarial therapy subsequent to which ascitis of the patient regressed. In this case, the clinical picture did not give a clue regarding the aetiology of the ascites. There was no evidence suggestive of filariasis, such as lymphoedema or hydrocele except mild eosinophilia. Circumstantialtial evidence regarding the aetiology of the effusion in our patient included her recovery following antifilarial therapy. The cytological diagnosis of Mf in this patient avoided further expensive investigations and the patient responded to antifilarial therapy.

摘要

据估计,全球有1.2亿人受到丝虫病的影响。在东南亚和南亚地区,班氏吴策线虫是导致丝虫病的最常见寄生虫,在99.4%的病例中出现。在本病例中,该寄生虫是一名年轻女性不明原因腹水的病因,其先前的细胞学报告性质可疑。广泛的体格检查和影像学评估无法确定腹水的病因。重复细胞学检查发现了一些班氏吴策线虫微丝蚴。该患者被诊断为低密度微丝蚴血症,并接受了抗丝虫治疗,随后患者的腹水消退。在这种情况下,临床表现并未提供有关腹水病因的线索。除轻度嗜酸性粒细胞增多外,没有证据提示丝虫病,如淋巴水肿或鞘膜积液。关于我们患者积液病因的间接证据包括她在抗丝虫治疗后的康复情况。该患者微丝蚴的细胞学诊断避免了进一步昂贵的检查,并且患者对抗丝虫治疗有反应。

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