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将质量实验室诊断纳入撒哈拉以南非洲疟疾控制议程。

Factoring quality laboratory diagnosis into the malaria control agenda for sub-Saharan Africa.

机构信息

Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.

出版信息

Am J Trop Med Hyg. 2013 Sep;89(3):403-6. doi: 10.4269/ajtmh.13-0108.

Abstract

Recent progress in malaria control in sub-Saharan Africa has been achieved primarily through provision of insecticide-treated nets, indoor residual spraying, and antimalarial drugs. Although these interventions are important, proper case identification and accurate measurement of their impact depend on quality diagnostic testing. Current availability of diagnostic testing for malaria in sub-Saharan Africa is inadequate to support disease management, prevention programs, and surveillance needs. Challenges faced include a dearth of skilled workforce, inadequate health systems infrastructure, and lack of political will. A coordinated approach to providing pre-service clinical and laboratory training together with systems that support a scale-up of laboratory services could provide means not only for effective malaria case management but also, management of non-malaria febrile illnesses, disease surveillance, and accurate control program evaluation. A synthesis of the challenges faced in ensuring quality malaria testing and how to include this information in the malaria control and elimination agenda are presented.

摘要

撒哈拉以南非洲地区在疟疾控制方面的最新进展主要是通过提供驱虫蚊帐、室内滞留喷洒和抗疟药物来实现的。尽管这些干预措施很重要,但正确的病例识别和对其影响的准确衡量取决于高质量的诊断检测。目前撒哈拉以南非洲地区疟疾诊断检测的可及性不足以支持疾病管理、预防规划和监测需求。面临的挑战包括缺乏熟练的劳动力、卫生系统基础设施不足以及缺乏政治意愿。协调提供职前临床和实验室培训以及支持实验室服务扩大的系统,可以不仅为有效管理疟疾病例,还为管理非疟疾发热疾病、疾病监测和准确的控制规划评估提供手段。本文综合了确保疟疾检测质量所面临的挑战,以及如何将这些信息纳入疟疾控制和消除议程。

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New global estimates of malaria deaths.疟疾死亡人数的新全球估计数。
Lancet. 2012 Aug 11;380(9841):559. doi: 10.1016/S0140-6736(12)61320-8.

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