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Am J Trop Med Hyg. 2013 Sep;89(3):403-6. doi: 10.4269/ajtmh.13-0108.
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本文引用的文献

1
New global estimates of malaria deaths.疟疾死亡人数的新全球估计数。
Lancet. 2012 Aug 11;380(9841):559. doi: 10.1016/S0140-6736(12)61320-8.
2
Global malaria mortality between 1980 and 2010: a systematic analysis.全球疟疾死亡率 1980 年至 2010 年:系统分析。
Lancet. 2012 Feb 4;379(9814):413-31. doi: 10.1016/S0140-6736(12)60034-8.
3
Major reduction in anti-malarial drug consumption in Senegal after nation-wide introduction of malaria rapid diagnostic tests.在塞内加尔全国范围内引入疟疾快速诊断检测后,抗疟药物的消耗大幅减少。
PLoS One. 2011 Apr 6;6(4):e18419. doi: 10.1371/journal.pone.0018419.
4
Rapid testing for malaria in settings where microscopy is available and peripheral clinics where only presumptive treatment is available: a randomised controlled trial in Ghana.在具备显微镜检查条件的环境和仅有经验性治疗的外围诊所中快速检测疟疾:加纳的一项随机对照试验。
BMJ. 2010 Mar 5;340:c930. doi: 10.1136/bmj.c930.
5
Community-wide benefits of targeted indoor residual spray for malaria control in the western Kenya highland.肯尼亚西部高地靶向室内滞留喷洒控制疟疾的全社区效益。
Malar J. 2010 Mar 3;9:67. doi: 10.1186/1475-2875-9-67.
6
Decreased in vitro susceptibility of Plasmodium falciparum isolates to artesunate, mefloquine, chloroquine, and quinine in Cambodia from 2001 to 2007.2001 至 2007 年柬埔寨青蒿琥酯、甲氟喹、氯喹和奎宁对疟原虫分离株的体外敏感性降低。
Antimicrob Agents Chemother. 2010 May;54(5):2135-42. doi: 10.1128/AAC.01304-09. Epub 2010 Mar 1.
7
Quality assurance of rapid diagnostic tests for malaria in routine patient care in rural Tanzania.坦桑尼亚农村常规患者护理中疟疾快速诊断检测的质量保证。
Am J Trop Med Hyg. 2010 Jan;82(1):151-5. doi: 10.4269/ajtmh.2010.09-0440.
8
Evidence of decline of malaria in the general hospital of Libreville, Gabon from 2000 to 2008.2000 年至 2008 年加蓬利伯维尔综合医院疟疾发病率下降的证据。
Malar J. 2009 Dec 17;8:300. doi: 10.1186/1475-2875-8-300.
9
Quality of malaria case management at outpatient health facilities in Angola.安哥拉门诊医疗机构疟疾病例管理质量。
Malar J. 2009 Dec 2;8:275. doi: 10.1186/1475-2875-8-275.
10
Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria.青蒿素类复方疗法:消除疟疾工作的重要工具。
Nat Rev Microbiol. 2009 Dec;7(12):864-74. doi: 10.1038/nrmicro2239. Epub 2009 Nov 2.

将质量实验室诊断纳入撒哈拉以南非洲疟疾控制议程。

Factoring quality laboratory diagnosis into the malaria control agenda for sub-Saharan Africa.

机构信息

Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.

出版信息

Am J Trop Med Hyg. 2013 Sep;89(3):403-6. doi: 10.4269/ajtmh.13-0108.

DOI:10.4269/ajtmh.13-0108
PMID:24006294
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3771273/
Abstract

Recent progress in malaria control in sub-Saharan Africa has been achieved primarily through provision of insecticide-treated nets, indoor residual spraying, and antimalarial drugs. Although these interventions are important, proper case identification and accurate measurement of their impact depend on quality diagnostic testing. Current availability of diagnostic testing for malaria in sub-Saharan Africa is inadequate to support disease management, prevention programs, and surveillance needs. Challenges faced include a dearth of skilled workforce, inadequate health systems infrastructure, and lack of political will. A coordinated approach to providing pre-service clinical and laboratory training together with systems that support a scale-up of laboratory services could provide means not only for effective malaria case management but also, management of non-malaria febrile illnesses, disease surveillance, and accurate control program evaluation. A synthesis of the challenges faced in ensuring quality malaria testing and how to include this information in the malaria control and elimination agenda are presented.

摘要

撒哈拉以南非洲地区在疟疾控制方面的最新进展主要是通过提供驱虫蚊帐、室内滞留喷洒和抗疟药物来实现的。尽管这些干预措施很重要,但正确的病例识别和对其影响的准确衡量取决于高质量的诊断检测。目前撒哈拉以南非洲地区疟疾诊断检测的可及性不足以支持疾病管理、预防规划和监测需求。面临的挑战包括缺乏熟练的劳动力、卫生系统基础设施不足以及缺乏政治意愿。协调提供职前临床和实验室培训以及支持实验室服务扩大的系统,可以不仅为有效管理疟疾病例,还为管理非疟疾发热疾病、疾病监测和准确的控制规划评估提供手段。本文综合了确保疟疾检测质量所面临的挑战,以及如何将这些信息纳入疟疾控制和消除议程。