Neuroassessment, Centre for Geographic Medicine Research, Coast/KEMRI Wellcome Trust Research Programme, Box 230, Kilifi 80108, Kenya.
Int J Environ Res Public Health. 2013 Sep 4;10(9):4132-42. doi: 10.3390/ijerph10094132.
The aim of the study was to investigate early executive functioning in young children from 6-35 months of age. The study involved 319 randomly selected children from the community, 17 HIV exposed but uninfected children and 31 HIV infected ARV-naive children. A variation of the A-not-B task was used. While there were no group differences in total correct, perseverative errors, nor maximum error run, a significant percentage of children were unable to complete the task as a consequence of the children becoming overtly distressed or refusing to continue. In a multivariate analysis we observed that the significant predictors of non-completion were HIV exposure (both infected and exposed) and being under 24 months of age. These patterns of results indicate that future work with a broader array of tasks need to look at the association of HIV and EF tasks and potential contribution of factors such as emotion regulation, persistence and motivation on performance on EF tasks.
本研究旨在探究 6-35 月龄幼儿的早期执行功能。该研究纳入了 319 名来自社区的随机儿童,其中包括 17 名 HIV 暴露但未感染儿童和 31 名 HIV 感染未经抗逆转录病毒治疗儿童。研究采用了 A-not-B 任务的变体。虽然在总正确、持续错误或最大错误运行方面,各组间无差异,但由于儿童表现出明显的痛苦或拒绝继续,相当比例的儿童无法完成任务。在多变量分析中,我们观察到非完成任务的显著预测因子是 HIV 暴露(感染和暴露)和年龄在 24 个月以下。这些结果模式表明,未来需要使用更广泛的任务来研究 HIV 和 EF 任务之间的关联,以及情绪调节、坚持和动机等因素对 EF 任务表现的潜在影响。