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术中手持式光学相干断层扫描前视探头：物理性能及初步动物成像

Intraoperative handheld optical coherence tomography forward-viewing probe: physical performance and preliminary animal imaging.

作者信息

Sun Cuiru, Lee Kenneth K C, Vuong Barry, Cusimano Michael D, Brukson Alexander, Mauro Antonio, Munce Nigel, Courtney Brian K, Standish Beau A, Yang Victor X D

出版信息

Biomed Opt Express. 2012 Jun 1;3(6):1404-12. doi: 10.1364/BOE.3.001404. Epub 2012 May 16.

DOI:10.1364/BOE.3.001404
PMID:22741085
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3370979/
Abstract

A prototype intraoperative hand-held optical coherence tomography (OCT) imaging probe was developed to provide micron resolution cross-sectional images of subsurface tissue during open surgery. This new ergonomic probe was designed based on electrostatically driven optical fibers, and packaged into a catheter probe in the form factor of clinically accepted Bayonet shaped neurosurgical probes. Optical properties of the probe were measured to have a ~20 μm spot size, 5 mm working distance and 4 mm field of view. Feasibility of this probe for structural and Doppler shift imaging was tested on porcine femoral blood vessel imaging.

摘要

开发了一种原型术中手持式光学相干断层扫描（OCT）成像探头，以在开放手术期间提供地下组织的微米级分辨率横截面图像。这种新型人体工程学探头基于静电驱动光纤进行设计，并包装成临床认可的卡口形神经外科探头外形的导管探头。经测量，该探头的光学特性为光斑尺寸约20μm、工作距离5mm和视野4mm。在猪股血管成像上测试了该探头用于结构和多普勒频移成像的可行性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/3370979/3763438210fc/boe-3-6-1404-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/3370979/6a7dd95fce1a/boe-3-6-1404-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/3370979/921d3991268b/boe-3-6-1404-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/3370979/0b6fc115d8ab/boe-3-6-1404-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/3370979/62f19899fab2/boe-3-6-1404-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/3370979/91ac755495dd/boe-3-6-1404-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/3370979/3763438210fc/boe-3-6-1404-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/3370979/6a7dd95fce1a/boe-3-6-1404-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/3370979/921d3991268b/boe-3-6-1404-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/3370979/0b6fc115d8ab/boe-3-6-1404-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/3370979/62f19899fab2/boe-3-6-1404-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/3370979/91ac755495dd/boe-3-6-1404-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/3370979/3763438210fc/boe-3-6-1404-g006.jpg

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本文引用的文献

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A forward-imaging needle-type OCT probe for image guided stereotactic procedures.一种用于图像引导立体定向手术的前向成像针型光学相干断层扫描探头。
Opt Express. 2011 Dec 19;19(27):26283-94. doi: 10.1364/OE.19.026283.
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Doppler optical coherence tomography for interventional cardiovascular guidance: in vivo feasibility and forward-viewing probe flow phantom demonstration.
迈向基于超高分辨率光学相干断层扫描的内镜下垂体腺和腺瘤筛查：性能参数评估
Biomed Opt Express. 2020 Nov 9;11(12):7003-7018. doi: 10.1364/BOE.409987. eCollection 2020 Dec 1.
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Review of intraoperative optical coherence tomography: technology and applications [Invited].术中光学相干断层扫描技术综述：技术与应用[特邀文章]
Biomed Opt Express. 2017 Feb 21;8(3):1607-1637. doi: 10.1364/BOE.8.001607. eCollection 2017 Mar 1.
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用于介入心血管引导的多普勒光学相干断层成像：体内可行性和前向观察探头流动体模演示。
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