Department of Plant and Microbial Biology, North Carolina State University, Raleigh, NC 27695, United States.
Curr Opin Plant Biol. 2013 Oct;16(5):554-60. doi: 10.1016/j.pbi.2013.08.001. Epub 2013 Sep 4.
The hormone ethylene plays numerous roles in plant development. In the last few years the model of ethylene signaling has evolved from an initially largely linear route to a much more complex pathway with multiple feedback loops. Identification of key transcriptional and post-transcriptional regulatory modules controlling expression and/or stability of the core pathway components revealed that ethylene perception and signaling are tightly regulated at multiple levels. This review describes the most current outlook on ethylene signal transduction and emphasizes the latest discoveries in the ethylene field that shed light on the mechanistic mode of action of the central pathway components CTR1 and EIN2, as well as on the post-transcriptional regulatory steps that modulate the signaling flow through the pathway.
激素乙烯在植物发育中扮演着多种角色。在过去的几年中,乙烯信号转导的模型已经从最初的线性途径演变为一个具有多个反馈回路的更为复杂的途径。识别出控制核心途径成分表达和/或稳定性的关键转录和转录后调控模块表明,乙烯的感知和信号转导在多个水平上受到严格的调控。本文综述了乙烯信号转导的最新观点,并强调了乙烯领域的最新发现,这些发现阐明了中心途径成分 CTR1 和 EIN2 的作用机制模式,以及调节信号通过途径的转录后调控步骤。