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近期发病的扩张型心肌病左心室功能恢复的流行病学及自然病程

Epidemiology and natural history of recovery of left ventricular function in recent onset dilated cardiomyopathies.

作者信息

Givertz Michael M, Mann Douglas L

机构信息

Cardiovascular Division, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, 02115, USA.

出版信息

Curr Heart Fail Rep. 2013 Dec;10(4):321-30. doi: 10.1007/s11897-013-0157-5.

Abstract

Although the long term prognosis of patients with dilated cardiomyopathy (DCM) remains poor, approximately 25 % of DCM patients with recent onset of heart failure (< 6 months) have a relatively benign clinical course with a spontaneously improvement in symptoms and partial, or in some cases complete, recovery of left ventricular (LV) function. Despite the longstanding recognition of the clinical phenomenon of LV recovery, relatively little attention has been paid to the etiology and natural history of this important group of DCM patients. Accordingly, in the present review we will focus on the epidemiology and natural history of recent onset DCM in patients who undergo spontaneous resolution of symptoms that is accompanied by recovery of LV function.

摘要

尽管扩张型心肌病(DCM)患者的长期预后仍然很差,但约25%近期发生心力衰竭(<6个月)的DCM患者临床病程相对良性,症状可自发改善,左心室(LV)功能部分恢复,或在某些情况下完全恢复。尽管LV恢复这一临床现象早已为人所知,但对于这一重要的DCM患者群体的病因和自然病史却相对关注较少。因此,在本综述中,我们将聚焦于近期发生DCM且症状自发缓解并伴有LV功能恢复的患者的流行病学及自然病史。

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