Legrand Delphine, Vaes Bert, Matheï Catharina, Swine Christian, Degryse Jean-Marie
IRSS Institute of Health and Society, Université Catholique de Louvain (UCL), Brussels, Belgium.
Age Ageing. 2013 Nov;42(6):727-34. doi: 10.1093/ageing/aft128. Epub 2013 Sep 7.
the prevalence of sarcopenia varies widely between studies. The objective of this study was to assess the prevalence of sarcopenia in a representative sample of persons aged 80 years and older according to the European Working Group on Sarcopenia in Older People (EWGSOP) algorithm and the proposed cut-off values. A secondary aim was to investigate the relationship between different individual criteria and low physical performance capacity.
baseline data of the prospective BELFRAIL study (BFC80+) were analysed. Sarcopenia status was determined according to the EWGSOP guidelines. The skeletal muscle mass index (SMI) was assessed according to bioelectrical impedance. Muscle strength and muscle performance were evaluated according to grip strength and the modified short physical performance battery (SPPBm). A logistic regression analysis was performed.
according to the EWGSOP algorithm, 12.5% of the participants were classified in the sarcopenia group. Sixty percent of the female participants had muscle strength values below the cut-off and 70% had low SPPBm values. In males, these prevalence values were 49.5% for grip strength and 39.7% for SPPB. The logistic regression analysis showed that low SPPBm was associated with grip strength (OR: 0.88, 95% CI: 0.84-0.92) independent of SMI.
in a population-based sample of the very old the prevalence of sarcopenia according to the EWGSOP algorithm is similar to the prevalence of sarcopenia with SMI as a single criterion. A large number of participants with a sufficient SMI value showed low muscle strength and/or a poor SPPBm score. A low SPPBm was associated with grip strength but not with SMI.
不同研究中肌肉减少症的患病率差异很大。本研究的目的是根据欧洲老年人肌肉减少症工作组（EWGSOP）的算法和建议的临界值，评估80岁及以上具有代表性人群样本中肌肉减少症的患病率。次要目的是研究不同个体标准与低身体运动能力之间的关系。
分析了前瞻性BELFRAIL研究（BFC80+）的基线数据。根据EWGSOP指南确定肌肉减少症状态。根据生物电阻抗评估骨骼肌质量指数（SMI）。根据握力和改良短身体性能量表（SPPBm）评估肌肉力量和肌肉性能。进行了逻辑回归分析。
根据EWGSOP算法，12.5%的参与者被归类为肌肉减少症组。60%的女性参与者肌肉力量值低于临界值，70%的女性SPPBm值较低。在男性中，握力的患病率为49.5%，SPPB的患病率为39.7%。逻辑回归分析表明，低SPPBm与握力相关（比值比：0.88，95%置信区间：0.84-0.92），独立于SMI。
在基于人群的高龄样本中，根据EWGSOP算法得出的肌肉减少症患病率与以SMI作为单一标准的肌肉减少症患病率相似。大量SMI值充足但肌肉力量低和/或SPPBm评分差的参与者。低SPPBm与握力相关，但与SMI无关。
