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洗必泰涂剂与药膜治疗慢性牙周炎的疗效比较

Comparison of the efficacy of chlorhexidine varnish and chip in the treatment of chronic periodontitis.

作者信息

Jagadish Pai B S, Rajan Smitha Anitha, Srinivas M, Padma R, Suragimath Girish, Walvekar Amit, Goel Saakshi, Kamath Vinesh

机构信息

Department of Periodontics, Coorg Institute of Dental Sciences, K. K. Campus, Maggula, Virajpet, South Coorg, Karnataka, India.

出版信息

Contemp Clin Dent. 2013 Apr;4(2):156-61. doi: 10.4103/0976-237X.114848.

Abstract

BACKGROUND

The purpose of this study was to clinically evaluate the benefits of sub gingival chlorhexidine (CHX) varnish and biodegradable CHX chip application used as an adjunct to scaling and root planning (SRP) as combined therapy and also to compare the effect of combined therapy with SRP alone.

MATERIALS AND METHODS

Fifteen patients with at least three sites with a probing pocket depth (PPD) of 5-8 mm were considered. Following baseline evaluation, all three sites were subjected for SRP. After completing SRP, each site was randomly subjected for CHX varnish, CHX chip application and the 3(rd) site was left without any medication as a control. Clinical parameters such as sulcus bleeding index, plaque index, bleeding on probing (BOP), PPD, and clinical attachment level (CAL) were recorded at baseline, 1 month and 3 months post-operatively.

RESULTS

All three groups presented with an improvement in clinical parameters compared to baseline. The mean reduction in PPD was 2.4 mm in SRP sites, 2.5 mm in SRP + CHX varnish sites and 2.8 mm in SRP + CHX chip sites. The mean gain in CAL was 2.4 mm in SRP sites, 2.3 mm in SRP + CHX varnish sites and 2.8 mm SRP + CHX chip sites.

INTERPRETATION AND CONCLUSION

The present study indicated that application of CHX varnish and placement of CHX chip as an adjunct to SRP produced a clinically significant reduction in the PPD, BOP and a gain in CAL at 30(th) day and 90(th) day from baseline when compared to SRP alone. The results though were not statistically significant.

摘要

背景

本研究的目的是临床评估龈下洗必泰(CHX)清漆和可生物降解的CHX芯片作为龈下刮治和根面平整(SRP)联合治疗辅助手段的益处,并比较联合治疗与单纯SRP的效果。

材料与方法

纳入15例患者,至少有3个探诊袋深度(PPD)为5 - 8mm的部位。在基线评估后,所有3个部位均接受SRP治疗。完成SRP后,每个部位随机接受CHX清漆、CHX芯片治疗,第3个部位不进行任何药物治疗作为对照。在基线、术后1个月和3个月记录临床参数,如龈沟出血指数、菌斑指数、探诊出血(BOP)、PPD和临床附着水平(CAL)。

结果

与基线相比,所有三组的临床参数均有改善。SRP部位PPD的平均减少量为2.4mm,SRP + CHX清漆部位为2.5mm,SRP + CHX芯片部位为2.8mm。SRP部位CAL的平均增加量为2.4mm,SRP + CHX清漆部位为2.3mm,SRP + CHX芯片部位为2.8mm。

解读与结论

本研究表明,与单纯SRP相比,应用CHX清漆和放置CHX芯片作为SRP的辅助手段,在基线后第30天和第90天可使PPD、BOP临床显著降低,CAL增加。尽管结果无统计学意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c029/3757875/32441e7f528f/CCD-4-156-g001.jpg

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