Mostafavi Ehsan, Chinikar Sadegh, Moradi Maryam, Bayat Neda, Meshkat Mohsen, Fard Mohammad Khalili, Ghiasi Seyyed Mojtaba
Department of Epidemiology, Pasteur Institute of Iran, Tehran, Iran.
Open Virol J. 2013 Aug 22;7:81-3. doi: 10.2174/1874357901307010081. eCollection 2013.
Crimean Congo hemorrhagic fever (CCHF) is a viral zoonosis, which is usually transmitted via tick bites or close contact with infected blood or tissue. This disease can cause a case fatality rate of up to 25%-30% in humans. CCHF Infection in birds is less documented. An ostrich can reproduce viruses and can also play the role of a mechanical vector, by transporting infected ticks without becoming ill. In March 2007, three butchers and one worker in an ostrich farm were infected with CCHF in central part of Iran. Considering the role ostriches play in transmitting the disease, serum samples from five ostriches of that farm were taken and sent to the laboratory for CCHF ELISA tests. The result of the IgG test was positive for one (20%) of the ostriches. At the same time, serum samples of eight sheep from the same farm were sent for IgG testing, two (25%) of which were positive. This was the first report of CCHF infection of an ostrich in Iran and tracing CCHF IgG against this ostrich and the afore-mentioned sheep may have revealed that the disease in the worker was the cause of transmission of this disease from these animals or their ticks.
克里米亚-刚果出血热(CCHF)是一种病毒性人畜共患病,通常通过蜱虫叮咬或与受感染的血液或组织密切接触传播。这种疾病在人类中的病死率可达25%-30%。鸟类感染CCHF的记录较少。鸵鸟能够繁殖病毒,还可作为机械传播媒介,携带感染的蜱虫而不发病。2007年3月,伊朗中部一家鸵鸟养殖场的三名屠夫和一名工人感染了CCHF。考虑到鸵鸟在传播该疾病中所起的作用,采集了该养殖场五只鸵鸟的血清样本并送往实验室进行CCHF ELISA检测。IgG检测结果显示其中一只鸵鸟(20%)呈阳性。同时,将来自同一养殖场的八只绵羊的血清样本送去进行IgG检测,其中两只(25%)呈阳性。这是伊朗首次报告鸵鸟感染CCHF,追踪针对这只鸵鸟和上述绵羊的CCHF IgG可能揭示该工人的疾病是由这些动物或其蜱虫传播所致。