Al-Hinai Ali T, Hassan Mohammed O, Simsek Mehmet, Al-Barwani Hameeda, Bayoumi Riad
Departments of Medicine.
J Sci Res Med Sci. 2002 Apr;4(1-2):25-7.
To describe the angiotensin converting enzyme (ACE) genotype frequencies among Omani Arabs.
A polymerase chain reaction (PCR) test, based on separation of different size DNA fragments, was developed to test the presence or absence (polymorphism) of a small DNA deletion in the ACE gene. The subjects were 124 Omani Arab students of Sultan Qaboos University, Muscat.
The frequency of the I allele was 0.29, while that of the D allele was 0.71. The gene frequency distribution did not deviate from Hardy-Weinberg equilibrium.
The frequency of D allele among Omanis is similar to that among other Arabs and Africans, but differs significantly from that among the Japanese and Chinese.
描述阿曼阿拉伯人中血管紧张素转换酶（ACE）基因型频率。
基于不同大小DNA片段的分离开发了一种聚合酶链反应（PCR）检测方法，以检测ACE基因中小DNA缺失的存在与否（多态性）。研究对象为马斯喀特苏丹卡布斯大学的124名阿曼阿拉伯学生。
I等位基因频率为0.29，而D等位基因频率为0.71。基因频率分布未偏离哈迪-温伯格平衡。
阿曼人中D等位基因频率与其他阿拉伯人和非洲人相似，但与日本人和中国人有显著差异。
