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生活方式干预可降低冠心病患者的心血管风险:一项随机临床试验。

Lifestyle interventions reduce cardiovascular risk in patients with coronary artery disease: a randomized clinical trial.

作者信息

Saffi Marco Aurélio Lumertz, Polanczyk Carisi Anne, Rabelo-Silva Eneida Rejane

机构信息

Graduate Program in Cardiology and Cardiovascular Sciences, Federal University of Rio Grande do Sul, Brazil Cardiovascular Division, Hospital de Clínicas de Porto Alegre, Brazil.

Graduate Program in Cardiology and Cardiovascular Sciences, Federal University of Rio Grande do Sul, Brazil Nursing School, Federal University of Rio Grande do Sul, Brazil

出版信息

Eur J Cardiovasc Nurs. 2014 Oct;13(5):436-43. doi: 10.1177/1474515113505396. Epub 2013 Sep 10.

Abstract

BACKGROUND

Nurse-led interventions have proven beneficial to reduce estimated cardiovascular risk.

AIM

The purpose of this study was to evaluate the effect of systematic, nurse-led individual lifestyle counseling sessions on the reduction of 10-year cardiovascular risk scores in patients with coronary artery disease (CAD).

METHODS

This was a randomized clinical trial of CAD patients treated at a tertiary referral hospital. The intervention group received nurse-led guidance by means of five face-to-face sessions and telephone contact over the course of one year, starting three months after hospital discharge. Exercise and dietary goals were set for each patient and monitored at each session. The control group received standard medical advice. Patients were stratified by Framingham risk score and compared at the end of the follow-up period.

RESULTS

The final sample comprised 74 patients, 38 in the intervention group and 36 in the control group. Mean age was 58 ± 9 years; 74% of patients were male. A 1.7 point (-13.6%) reduction in risk score was recorded in the intervention group, vs a 1.2 point increase in risk score (+11%) in the control group (p=0.011). Significant between-group differences were detected for weight (intervention, 78 ± 14 kg at baseline vs 77 ± 14 kg at study end; control, 78 ± 15 kg vs 79 ± 15 kg; p=0.04), systolic blood pressure (intervention, 136 ± 22 mm Hg vs 124 ± 15 mm Hg; control, 126 ± 15 mm Hg vs 129 ± 16 mm Hg; p=0.005), and diastolic blood pressure (intervention, 82 ± 10 mm Hg vs 77 ± 09 mm Hg; control, 79 ± 09 mm Hg vs 80 ± 10 mm Hg; p=0.02).

CONCLUSION

Structured and systematic nurse-led lifestyle counseling effectively reduced cardiovascular risk score.

摘要

背景

由护士主导的干预措施已被证明有助于降低估计的心血管疾病风险。

目的

本研究旨在评估由护士系统地、一对一地主导生活方式咨询对降低冠心病(CAD)患者10年心血管疾病风险评分的效果。

方法

这是一项针对在三级转诊医院接受治疗的CAD患者的随机临床试验。干预组在出院三个月后开始,在一年的时间里通过五次面对面咨询和电话联系接受护士主导的指导。为每位患者设定运动和饮食目标,并在每次咨询时进行监测。对照组接受标准医疗建议。患者按弗雷明汉风险评分分层,并在随访期结束时进行比较。

结果

最终样本包括74名患者,干预组38名,对照组36名。平均年龄为58±9岁;74%的患者为男性。干预组的风险评分降低了1.7分(-13.6%),而对照组的风险评分增加了1.2分(+11%)(p=0.011)。在体重方面检测到显著的组间差异(干预组,基线时为78±14千克,研究结束时为77±14千克;对照组,78±15千克对79±15千克;p=0.04),收缩压(干预组,136±22毫米汞柱对124±15毫米汞柱;对照组,126±15毫米汞柱对129±16毫米汞柱;p=0.005),以及舒张压(干预组,82±10毫米汞柱对77±9毫米汞柱;对照组,79±9毫米汞柱对80±10毫米汞柱;p=0.02)。

结论

由护士主导的结构化、系统化生活方式咨询有效地降低了心血管疾病风险评分。

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