Explicet：用于元数据驱动的微生物组数据管理、分析和可视化的图形用户界面软件。
Explicet: graphical user interface software for metadata-driven management, analysis and visualization of microbiome data.
机构信息
Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA, University of Colorado Microbiome Research Consortium, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, CO 80045, USA, Incubix Incorporated, Boulder, CO 80301, USA and Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
出版信息
Bioinformatics. 2013 Dec 1;29(23):3100-1. doi: 10.1093/bioinformatics/btt526. Epub 2013 Sep 10.
Abstract
Studies of the human microbiome, and microbial community ecology in general, have blossomed of late and are now a burgeoning source of exciting research findings. Along with the advent of next-generation sequencing platforms, which have dramatically increased the scope of microbiome-related projects, several high-performance sequence analysis pipelines (e.g. QIIME, MOTHUR, VAMPS) are now available to investigators for microbiome analysis. The subject of our manuscript, the graphical user interface-based Explicet software package, fills a previously unmet need for a robust, yet intuitive means of integrating the outputs of the software pipelines with user-specified metadata and then visualizing the combined data.
摘要
近年来，人类微生物组学和微生物群落生态学的研究蓬勃发展，成为令人兴奋的研究发现的新兴来源。随着下一代测序平台的出现，极大地扩展了微生物组相关项目的范围，现在有几个高性能的序列分析管道（例如 QIIME、MOTHUR、VAMPS）可供研究人员进行微生物组分析。我们的手稿的主题，基于图形用户界面的 Explicet 软件包，填补了以前未满足的需求，即提供一种强大而直观的方法，将软件管道的输出与用户指定的元数据集成，然后可视化组合数据。
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