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驾驶机动性导致认知衰退的轨迹:来自健康与退休研究的证据。

Trajectories of cognitive decline by driving mobility: evidence from the Health and Retirement Study.

作者信息

Choi Moon, Lohman Matthew C, Mezuk Briana

机构信息

College of Social Work, University of Kentucky, Lexington, KY, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA.

出版信息

Int J Geriatr Psychiatry. 2014 May;29(5):447-53. doi: 10.1002/gps.4024. Epub 2013 Sep 10.

DOI:10.1002/gps.4024
PMID:24022894
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4080895/
Abstract

OBJECTIVE

The recent emphasis of the importance of "aging in place" has highlighted the role of transportation in health promotion over the life course. Driving cessation in later life is associated with numerous poor health outcomes including limitations in social and physical functioning and increased risk of mortality. However, little is known about the relationship between driving cessation and change in cognitive functioning in late life. This study examined the association between driving mobility and trajectories of cognitive functioning among older adults.

METHODS

Using data from six waves [1998-2008] of the Health and Retirement Study, trajectories of cognitive functioning were estimated over a 10-year period using longitudinal mixed effects models [N = 9,135]. Cognitive function was assessed with a modified version of the Telephone Interview for Cognitive Status. Driving status and health characteristics were assessed by self-report.

RESULTS

Older adults who did not drive (former and never drivers) at baseline had lower average cognitive scores compared with active drivers. Former drivers had accelerated cognitive decline over the subsequent 10 years compared with active drivers (β = -0.35, 95% Confidence Interval [CI] = -0.43 to -0.26) even after controlling for baseline cognitive functioning and health status. The transition to non-driving was associated with a faster cognitive decline among those who were driving at baseline (β = -0.31, 95% CI = -0.40 to -0.22).

CONCLUSIONS

Older adults without driving mobility had poorer cognitive functioning at baseline and experienced accelerated cognitive decline relative to active drivers over follow-up.

摘要

目的

近期对“就地养老”重要性的强调凸显了交通在整个生命历程中促进健康方面的作用。晚年停止驾车与众多不良健康后果相关,包括社交和身体功能受限以及死亡风险增加。然而,对于晚年停止驾车与认知功能变化之间的关系知之甚少。本研究调查了老年人驾驶机动性与认知功能轨迹之间的关联。

方法

利用健康与退休研究六轮(1998 - 2008年)的数据,使用纵向混合效应模型在10年期间估计认知功能轨迹[N = 9,135]。认知功能通过认知状态电话访谈的修改版进行评估。驾驶状态和健康特征通过自我报告进行评估。

结果

与现职驾驶员相比,基线时不驾车的老年人(曾经驾车者和从未驾车者)平均认知得分较低。即使在控制了基线认知功能和健康状况之后,曾经驾车者在随后10年中的认知衰退速度也比现职驾驶员快(β = -0.35,95%置信区间[CI] = -0.43至 -0.26)。从驾车到不驾车的转变与基线时驾车的人群中更快的认知衰退相关(β = -0.31,95% CI = -0.40至 -0.22)。

结论

没有驾驶机动性的老年人在基线时认知功能较差,并且在随访期间相对于现职驾驶员经历了加速的认知衰退。

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