Nanobacterie société à responsabilité limitée , Paris , France and.
Int J Hyperthermia. 2013 Dec;29(8):801-9. doi: 10.3109/02656736.2013.821527. Epub 2013 Sep 11.
We review the most recent and significant results published in the field of magnetotactic bacteria (MTB), in particular data relating to the use of bacterial magnetosomes in magnetic hyperthermia for the treatment of tumours. We review different methods for cultivating MTB and preparing suspensions of bacterial magnetosomes. As well as the production of magnetosomes, we also review key data on the toxicity of the magnetosomes as well as their heating and anti-tumour efficiencies. The toxicity and efficiency of magnetosomes needs to be understood and the risk-benefit ratio with which to evaluate their use in the magnetic hyperthermia treatment of tumours needs to be measured.
我们回顾了在磁细菌（MTB）领域发表的最新和最重要的结果，特别是与利用细菌磁小体进行磁热疗治疗肿瘤相关的数据。我们回顾了培养 MTB 和制备细菌磁小体悬浮液的不同方法。除了磁小体的产生，我们还回顾了关于磁小体毒性及其加热和抗肿瘤效率的关键数据。需要了解磁小体的毒性和效率，并需要衡量其用于肿瘤磁热疗的风险效益比。
