Kolstad H A, Brandt L P, Rasmussen K
Aarthus Universitet, Socialmedicinsk Institut.
Ugeskr Laeger. 1990 Aug 27;152(35):2481-2.
Workers in the dry-cleaning industry are exposed to vapours from the cleaning fluids, primarily perchlorethylene, which is a chlorinated solvent. Animal experiments, short-term tests for mutagenic effects and epidemiological investigations have raised the suspicion that perchlorethylene may cause reproductive failure. This investigation is an attempt to assess the risk for reproductive failure in 886 women exposed to dry-cleaning solvents while employed in dry-cleaning establishments. Twelve spontaneous abortions occurred, one infant was born with malformations and ten infants had low birth weights. A non-significant risk for spontaneous abortion was found among women with the greatest exposure. This estimate is, however, uncertain and the result must be interpreted with care.
干洗行业的工人会接触到清洗液产生的蒸汽，主要是全氯乙烯，它是一种氯化溶剂。动物实验、致突变作用的短期测试以及流行病学调查引发了人们对全氯乙烯可能导致生殖功能衰竭的怀疑。这项调查旨在评估886名在干洗店工作且接触干洗溶剂的女性出现生殖功能衰竭的风险。发生了12例自然流产，1名婴儿出生时伴有畸形，10名婴儿出生体重低。在接触程度最高的女性中发现自然流产风险不显著。然而，这一估计并不确定，结果必须谨慎解读。
