Department of Orthopedic Surgery, Research Group for Kinematics and Biomechanics, University of Frankfurt, 60528, Frankfurt, Germany.
Knee Surg Sports Traumatol Arthrosc. 2014 Jun;22(6):1353-9. doi: 10.1007/s00167-013-2686-6. Epub 2013 Sep 18.
The purpose of this study was to investigate the effect of a 6-month period of intensive running followed by the participation at a marathon run on cartilage volume and thickness in knees of marathon beginners.
Ten asymptomatic marathon beginners underwent a supervised 6-month training program, which was finalized by the participation at a marathon run. Three-dimensional quantitative magnetic resonance imaging was performed before the training program (baseline measurements) and 1 day after the marathon (follow-up measurements). Cartilage volume and thickness of the medial and lateral femur, medial and lateral tibia, and patella were measured using semiautomated cartilage segmentation and three dimensional data postprocessing.
Significant differences between baseline and follow-up measurements were observed at the lateral femur, where cartilage volume and thickness decreased by a mean of 3.2 ± 3.0% (p = 0.012) and 1.7 ± 1.6% (p = 0.010), respectively. No significant changes in cartilage volume and thickness were observed at the medial and lateral tibia, the medial femur, and the patella.
Significant cartilage loss was observed at the lateral femur; however, the measured values are comparable to previously reported precision errors for quantitative cartilage measurement and thus most likely not of clinical relevance. High-impact forces during long-distance running are well tolerated even in marathon beginners and do not lead to clinical relevant cartilage loss.
IV.
本研究旨在探讨 6 个月的强化跑步训练后参加马拉松对马拉松初学者膝关节软骨体积和厚度的影响。
10 名无症状的马拉松初学者接受了为期 6 个月的监督训练计划，最后参加了马拉松比赛。在训练计划前（基线测量）和马拉松比赛后 1 天（随访测量）进行了三维定量磁共振成像。使用半自动软骨分割和三维数据后处理技术测量了股骨内外侧、胫骨内外侧和髌骨的软骨体积和厚度。
在外侧股骨上，基线测量和随访测量之间观察到显著差异，软骨体积和厚度分别减少了 3.2±3.0%（p=0.012）和 1.7±1.6%（p=0.010）。在胫骨内外侧、股骨内外侧和髌骨上，软骨体积和厚度均无显著变化。
在外侧股骨上观察到明显的软骨丢失，但测量值与定量软骨测量的先前报道的精度误差相当，因此很可能没有临床意义。即使在马拉松初学者中，长距离跑步产生的高冲击力也能很好地耐受，不会导致临床相关的软骨丢失。
IV。
