Birner B, Tourtas T, Wessel J M, Jünemann A G, Mardin C Y, Kruse F E, Laemmer R
Augenklinik, Friedrich-Alexander Universität Erlangen-Nürnberg, Schwabachanlage 6, 91054, Erlangen, Deutschland.
Ophthalmologe. 2014;111(7):638-43. doi: 10.1007/s00347-013-2943-6.
The purpose of this study was to analyze if anterior chamber parameters are risk factors for the development of pigment dispersion syndrome (PDS) and/or for the conversion to pigmentary glaucoma (PG).
This study included a total of 63 eyes from 35 patients with PDS and PG and 65 eyes from 49 unaffected volunteers as the control group. The following parameters were measured by slit lamp optical coherence tomography (SL-OCT): anterior chamber volume (ACV) and depth (ACD), angle opening distance (AOD) and the trabecular iris space area (TISA) at 500 µm and 750 μm from the scleral spur. Comparisons between the following groups were performed: between the PDS/PG and the control group, between PDS and PG and between male and female patients.
The results of ACV, ACD, AOD and TISA were significantly higher in PDS/PG patients when compared to the control group. There were no significant differences between PDS and PG. The gender-specific comparison also showed no significant differences.
Significantly higher anterior chamber parameters are a possible risk factor for development of PDS; however, a higher risk of conversion to PG does not seem to correlate with increased anterior chamber parameters. The parameters of the anterior chamber are apparently not associated with the male predominance of PDS and PG.
本研究旨在分析前房参数是否为色素播散综合征（PDS）发生和/或转化为色素性青光眼（PG）的危险因素。
本研究共纳入35例PDS和PG患者的63只眼，以及49名未受影响志愿者的65只眼作为对照组。通过裂隙灯光学相干断层扫描（SL - OCT）测量以下参数：前房容积（ACV）和深度（ACD）、房角开放距离（AOD）以及距巩膜突500 µm和750 µm处的小梁虹膜空间面积（TISA）。对以下几组进行比较：PDS/PG组与对照组之间、PDS组与PG组之间以及男性和女性患者之间。
与对照组相比，PDS/PG患者的ACV、ACD、AOD和TISA结果显著更高。PDS组和PG组之间无显著差异。按性别比较也无显著差异。
前房参数显著更高可能是PDS发生的危险因素；然而，转化为PG的较高风险似乎与前房参数增加无关。前房参数显然与PDS和PG的男性优势无关。
