Rallan M, Chaudhary S, Goswami M, Sinha A, Arora R, Kishor A
Department of Paedodontics, Teerthanker Mahaveer Dental College and Research Centre, Moradabad, 244001, Uttar Pradesh, India,
Eur Arch Paediatr Dent. 2013 Oct;14(5):313-8. doi: 10.1007/s40368-013-0085-9. Epub 2013 Sep 26.
To determine the effect of three remineralising agents on human primary anterior teeth, i.e. CPP-ACP, CPP-ACPF, fluoridated toothpaste and artificial saliva as control.
Forty primary maxillary anterior teeth were divided into four groups: Group I: CPP-ACP, Group II: CPP-ACPF and Group III: fluoridated toothpaste as experimental and Group IV: artificial saliva as control. The samples were immersed in cola soft drink and artificial saliva for 10 cycles of 5 s each. After erosive procedure, a thin layer of CPP-ACP, CPP-ACPF or fluoridated toothpaste were applied to the tooth surfaces for 3 min, and kept in artificial saliva for 8 h. Samples in the control group were directly kept in artificial saliva without any treatment. The Knoop microhardness of the labial surface of enamel was measured at baseline, after erosion and after the remineralisation procedures.
No significant differences were observed among the different groups at pre-erosion and post-erosion intervals. However, after remineralisation, mean microhardness in different groups was significantly higher in Group II as compared to all the other groups (p < 0.001). Group IV had significantly lower mean microhardness as compared to all the other groups (p < 0.001).
The collected data were statistically analysed using ANOVA test followed by Tukey's HSD test as the post-hoc tests to compare the differences in mean microhardness at different time intervals. Paired t test was used to assess the change in mean microhardness within a group.
CPP-ACPF showed the best remineralisation potential.
确定三种再矿化剂对人类乳上前牙的影响，即酪蛋白磷酸肽-无定形磷酸钙（CPP-ACP）、酪蛋白磷酸肽-无定形磷酸钙氟化物（CPP-ACPF）、含氟牙膏，并以人工唾液作为对照。
40颗上颌乳前牙被分为四组：第一组：CPP-ACP；第二组：CPP-ACPF；第三组：含氟牙膏作为实验组；第四组：人工唾液作为对照组。将样本浸入可乐软饮料和人工唾液中，进行10个循环，每个循环5秒。侵蚀处理后，将一层薄薄的CPP-ACP、CPP-ACPF或含氟牙膏涂覆在牙齿表面3分钟，然后置于人工唾液中8小时。对照组的样本未经任何处理直接置于人工唾液中。在基线、侵蚀后和再矿化处理后，测量釉质唇面的努氏显微硬度。
在侵蚀前和侵蚀后的时间段内，不同组之间未观察到显著差异。然而，再矿化后，第二组的平均显微硬度显著高于所有其他组（p<0.001）。第四组的平均显微硬度显著低于所有其他组（p<0.001）。
收集的数据使用方差分析进行统计学分析，随后使用图基事后检验来比较不同时间间隔下平均显微硬度的差异。配对t检验用于评估组内平均显微硬度的变化。
CPP-ACPF显示出最佳的再矿化潜力。
