新生儿惊厥作为未被识别的母亲甲状旁腺功能亢进的一种表现。
Neonatal seizure as a manifestation of unrecognized maternal hyperparathyroidism.
作者信息
Korkmaz Hüseyin Anıl, Ozkan Behzat, Terek Demet, Dizdarer Ceyhun, Arslanoğlu Sertaç
机构信息
Dr. Behçet Uz Children Disease and Surgery Training and Research Hospital, Department of Pediatric Endocrinology, İzmir, Turkey. E-mail:
出版信息
J Clin Res Pediatr Endocrinol. 2013 Sep 10;5(3):206-8. doi: 10.4274/Jcrpe.1037.
Abstract
Maternal hypercalcemia suppresses parathyroid activity in the fetus resulting in impaired parathyroid responsiveness to hypocalcemia after birth. Resultant hypocalcemia may be severe and prolonged and rarely may lead to convulsions. Here, we present a newborn infant admitted to the pediatric emergency department at age two weeks with recurrent tonic convulsions due to asymptomatic maternal hyperparathyroidism and vitamin D deficiency. Physicians should be aware that undiagnosed maternal hyperparathyroidism can cause severe hypocalcemia in the newborn.
摘要
母体高钙血症会抑制胎儿的甲状旁腺活动，导致出生后甲状旁腺对低钙血症的反应性受损。由此产生的低钙血症可能严重且持续时间长，很少会导致惊厥。在此，我们报告一名两周大的新生儿因无症状性母体甲状旁腺功能亢进和维生素D缺乏而反复出现强直性惊厥，被收入儿科急诊科。医生应意识到，未被诊断出的母体甲状旁腺功能亢进可导致新生儿严重低钙血症。
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