Gheshmi Abdolmajid Nazemi, Naderi Salma, Homayrani Elham, Safari Batool
M.D., Pediatrician, Assistant Professor, Department of Pediatrics, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
M.D., Neonatologist, Assistant Professor, Division of Neonatology, Department of Pediatrics, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Electron Physician. 2015 Oct 19;7(6):1387-90. doi: 10.14661/1387. eCollection 2015 Oct.
Hyperbilirubinemia is one of the most common problems in newborns, and it is reported in about 60% of infants. Phototherapy is used extensively to treat these patients, and hypocalcemia is one important side effect of the phototherapy. The aim of this study was to determine the prevalence of hypocalcemia after phototherapy in full-term newborns that underwent phototherapy in Koodakan Hospital in Bandar Abbas in 2013.
This cross-sectional study was conducted on 100 neonates admitted to Koodakan Hospital in Bandar Abbas. All of the newborns were full-term, healthy, weighed more than 2,500 g, and were candidates for phototherapy. The newborns were divided into two groups, i.e., 1) those who were more than three days old and 2) those who were less than three days old. Serum bilirubin and calcium levels were measured for each newborn before phototherapy and 48 hours after phototherapy, and the before and after levels were compared. The data were analyzed using IBM SPSS 21.0 statistical software. The Fisher Exact test, the independent samples t-test, and the paired t-test were used to test the research hypothesis.
Among the 100 newborns studied, 54% had decreased calcium levels after phototherapy. The prevalence of hypocalcemia was 9% in this study, and the prevalence was not significantly different in the two age groups (P = 0.217).
Phototherapy does not increase the risk of hypocalcemia in healthy, full-term neonates. Therefore, prophylactic calcium is not recommended for healthy, full-term neonates who have undergone phototherapy.
高胆红素血症是新生儿最常见的问题之一，约60%的婴儿有此症状。光疗被广泛用于治疗这些患儿，低钙血症是光疗的一个重要副作用。本研究的目的是确定2013年在阿巴斯港库达坎医院接受光疗的足月新生儿光疗后低钙血症的患病率。
本横断面研究对100名入住阿巴斯港库达坎医院的新生儿进行。所有新生儿均为足月、健康，体重超过2500克，且为光疗候选对象。新生儿被分为两组，即1）年龄超过三天的新生儿和2）年龄小于三天的新生儿。在光疗前及光疗48小时后测量每个新生儿的血清胆红素和钙水平，并比较前后水平。数据使用IBM SPSS 21.0统计软件进行分析。采用Fisher精确检验、独立样本t检验和配对t检验来检验研究假设。
在研究的100名新生儿中，54%的新生儿光疗后钙水平下降。本研究中低钙血症的患病率为9%，两个年龄组的患病率无显著差异（P = 0.217）。
光疗不会增加健康足月新生儿发生低钙血症的风险。因此，不建议对接受光疗的健康足月新生儿预防性补钙。
