Gastroenterology Division, Yokohama City University School of Medicine, Yokohama, Japan.
Gut Liver. 2013 Sep;7(5):532-8. doi: 10.5009/gnl.2013.7.5.532. Epub 2013 Jun 11.
BACKGROUND/AIMS: Left-sided diverticulitis is increasing in Japan, and many studies report that left-sided diverticulitis is more likely to be severe. Therefore, it is important to identify the features and risk factors for left-sided diverticulitis. We hypothesized that left-sided diverticulitis in Japan is related to obesity and conducted a study of the features and risk factors for this disorder in Japan.
Right-sided diverticulitis and left-sided diverticulitis patients (total of 215) were compared with respect to background, particularly obesity-related factors to identify risk factors for diverticulitis.
There were 166 (77.2%) right-sided diverticulitis patients and 49 (22.8%) left-sided diverticulitis patients. The proportions of obese patients (body mass index ≥25 kg/m(2), p=0.0349), viscerally obese patients (visceral fat area ≥100 cm(2), p=0.0019), patients of mean age (p=0.0003), and elderly patients (age ≥65 years, p=0.0177) were significantly higher in the left-sided-diverticulitis group than in the right-sided-diverticulitis group. The proportion of viscerally obese patients was significantly higher in the left-sided-diverticulitis group than in the left-sided-diverticulosis group (p=0.0390).
This study showed that obesity, particularly visceral obesity, was a risk factor for left-sided diverticulitis in Japan.
背景/目的：日本左侧憩室炎的发病率正在增加，许多研究报告称左侧憩室炎更易严重。因此，识别左侧憩室炎的特征和危险因素非常重要。我们假设日本左侧憩室炎与肥胖有关，并对日本左侧憩室炎的特征和危险因素进行了研究。
比较了右侧憩室炎和左侧憩室炎患者（共 215 例）的背景，特别是与肥胖相关的因素，以确定憩室炎的危险因素。
右侧憩室炎患者 166 例（77.2%），左侧憩室炎患者 49 例（22.8%）。肥胖患者（BMI≥25 kg/m2，p=0.0349）、内脏肥胖患者（内脏脂肪面积≥100 cm2，p=0.0019）、平均年龄患者（p=0.0003）和老年患者（年龄≥65 岁，p=0.0177）的比例在左侧憩室炎组显著高于右侧憩室炎组。内脏肥胖患者的比例在左侧憩室炎组显著高于左侧憩室炎组（p=0.0390）。
本研究表明，肥胖，特别是内脏肥胖，是日本左侧憩室炎的危险因素。
