Institute of Biochemistry, Food Science and Nutrition, Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot 76100, Israel.
Ageing Res Rev. 2013 Sep;12(4):931-40. doi: 10.1016/j.arr.2013.09.002. Epub 2013 Sep 25.
Life span extension has been a goal of research for several decades. Resetting circadian rhythms leads to well being and increased life span, while clock disruption is associated with increased morbidity accelerated aging. Increased longevity and improved health can be achieved by different feeding regimens that reset circadian rhythms and may lead to better synchrony in metabolism and physiology. This review focuses on the circadian aspects of energy metabolism and their relationship with aging in mammals.
寿命延长一直是几十年来研究的目标。重置生物钟节律可带来健康和寿命的延长，而生物钟紊乱则与发病率增加和衰老加速有关。通过重置生物钟节律的不同喂养方案可以实现寿命的延长和健康状况的改善，并且可能导致代谢和生理学的更好同步。本文综述了哺乳动物能量代谢的生物钟方面及其与衰老的关系。
