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昼夜节律、衰老与哺乳动物的寿命。

Circadian rhythms, aging, and life span in mammals.

机构信息

Institute of Biochemistry, Food Science and Nutrition, Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel.

出版信息

Physiology (Bethesda). 2011 Aug;26(4):225-35. doi: 10.1152/physiol.00012.2011.

DOI:10.1152/physiol.00012.2011
PMID:21841071
Abstract

Resetting the circadian clock leads to well being and increased life span, whereas clock disruption is associated with aging and morbidity. Increased longevity and improved health can be achieved by different feeding regimens that reset circadian rhythms and may lead to better synchrony in metabolism and physiology. This review focuses on recent findings concerning the relationships between circadian rhythms, aging attenuation, and life-span extension in mammals.

摘要

重置生物钟可带来健康和延长寿命,而生物钟紊乱则与衰老和发病相关。通过重置生物钟的不同喂养方案可实现寿命延长和健康改善,这可能导致代谢和生理的同步性更好。本文重点介绍了关于哺乳动物中生物钟、衰老衰减和寿命延长之间关系的最新发现。

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