Ren Ling-yan, He Yan, Zhang Ting, Wang Chan-juan, Guan Zhi-zhong, Shan Keren
Key Laboratory of Molecular Biology, Guiyang Medical University, Guiyang, Guizhou 550004, P. R. China. Email:
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2013 Oct;30(5):626-31. doi: 10.3760/cma.j.issn.1003-9406.2013.05.027.
To analyze the population genetics characteristics of mitochondrial DNA (mtDNA) in Gelao, Mulao, Maonan ethnic groups from Guizhou.
Minisequenceing and restriction fragment length polymorphism (RFLP) were used to analyze 12 single nucleotide polymorphism (SNPs) of mitochondrial DNA in the 3 ethnic groups.
A total of 30 haplotypes were detected in 156 samples. The distribution of H1, H23 had differed between Mulao, Maonan and Gelao, respectively, and so did M7 among the three groups. The difference was statistically significant (P < 0.05). Mulao, Maonan had respectively differed from Gelao and the difference was also statistically significant (P < 0.05).
There was a great similarity in the distribution of haplotypes of the mtDNA among the three ethnic groups, except for some difference in the distribution of certain haplotypes.
分析贵州仡佬族、毛南族、仫佬族线粒体DNA（mtDNA）的群体遗传学特征。
采用小序列分析和限制性片段长度多态性（RFLP）技术分析3个民族线粒体DNA的12个单核苷酸多态性（SNP）。
156份样本中共检测到30种单倍型。H1、H23在仫佬族、毛南族和仡佬族中的分布分别存在差异，M7在三组中的分布也存在差异。差异具有统计学意义（P<0.05）。仫佬族、毛南族分别与仡佬族存在差异，且差异也具有统计学意义（P<0.05）。
三个民族mtDNA单倍型分布存在较大相似性，但部分单倍型分布存在一定差异。
