Warsaw University of Technology, Noakowskiego 3, 00-664 Warsaw, Poland.
Biomed Res Int. 2013;2013:168512. doi: 10.1155/2013/168512. Epub 2013 Sep 2.
Uraemic toxins-creatol and N-methylguanidine-are generated in conversion of creatinine in water in the presence of various forms of carbon such as fullerene C60, carbon-encapsulated magnetic nanoparticles, and multiwalled carbon nanotubes and oxygen. The conversion degree for creatinine was different for fullerene C60, CEMNPs, and MWCNTs and was 9% (3.6% creatol, 5.4% N-methylguanidine), 35% (12% creatol, 23% N-methylguanidine), and 75% (16% creatol, 59% N-methylguanidine), respectively.
尿毒毒素——肌酐和 N-甲基胍——是在水存在的情况下,由各种形式的碳(如富勒烯 C60、碳包被的磁性纳米粒子和多壁碳纳米管)和氧气转化肌酐生成的。富勒烯 C60、CEMNPs 和 MWCNTs 对肌酐的转化率分别为 9%(3.6%肌酐,5.4%N-甲基胍)、35%(12%肌酐,23%N-甲基胍)和 75%(16%肌酐,59%N-甲基胍)。