Araujo Liliana, Moujir Laila M, Rojas Janne, Rojas Luis, Carmona Juan, Rondón María
Microbiology and Cell Biology Department, University of La Laguna, La Laguna, Tenerife, Spain.
Nat Prod Commun. 2013 Aug;8(8):1175-8.
The essential oil from aerial parts of Conyza bonariensis (L) Cronquist collected in Mérida was obtained by hydrodistillation and analysed by GC/MS. The major components were trans-beta-farnesene (37.8%), trans-ocimene (20.7%) and beta-sesquiphellandrene (9.8%). Cytotoxicity assay was also performed with the essential oil against HeLa (cervix carcinoma), A-459 (lung carcinoma) and MCF-7 (breast adenocarcinoma) human cell lines and against normal Vero cells (African green monkey kidney) with IC50 values ranging from 1.4 to 45.8 microg/mL. Additionally, the essential oil presented a significant bactericidal effect against Bacillus cereus, while a moderate activity was observed against Staphylococcus epidermidis and Candida albicans.
对在梅里达采集的牛膝菊地上部分的精油进行水蒸馏提取，并通过气相色谱/质谱联用仪进行分析。主要成分是反式-β-法尼烯（37.8%）、反式罗勒烯（20.7%）和β-倍半水芹烯（9.8%）。还用该精油对人宫颈癌细胞系HeLa、人肺癌细胞系A-459和人乳腺腺癌细胞系MCF-7以及正常非洲绿猴肾细胞系Vero进行了细胞毒性试验，半数抑制浓度值在1.4至45.8微克/毫升之间。此外，该精油对蜡样芽孢杆菌有显著杀菌作用，对表皮葡萄球菌和白色念珠菌有中等活性。
