Murphy M J, Torstensson P A
DermaLase Training Services, Glasgow, UK,
Lasers Med Sci. 2014 May;29(3):973-8. doi: 10.1007/s10103-013-1445-8. Epub 2013 Oct 2.
Thermal relaxation times were introduced into modern skin-laser science with the inception of selective photothermolysis. As a result, laser pulsewidths were determined according to the thermal relaxation times of the tissue targets. The Arrhenius Damage Integral shows that this approach is incorrect. The important parameter is the time required to induce irreversible protein denaturation within the target. This time is determined by the tissue's intrinsic structure, not its physical dimensions. This report explains why thermal relaxation times should not be considered when treating many skin conditions with lasers or IPL systems.
随着选择性光热作用的出现，热弛豫时间被引入现代皮肤激光科学领域。因此，激光脉冲宽度是根据组织靶点的热弛豫时间来确定的。阿累尼乌斯损伤积分表明这种方法是不正确的。重要的参数是在靶点内诱导不可逆蛋白质变性所需的时间。这个时间是由组织的固有结构决定的，而不是其物理尺寸。本报告解释了在用激光或强脉冲光（IPL）系统治疗多种皮肤疾病时，为何不应考虑热弛豫时间。
