Lee Jun Wook, Kim Young Joon, Kim Hoon, Nam Sang Hyun, Shin Bo Moon, Choi Young Woong
Department of Plastic and Reconstructive Surgery, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
Arch Plast Surg. 2013 Sep;40(5):536-41. doi: 10.5999/aps.2013.40.5.536. Epub 2013 Sep 13.
Pathogens in the nasal cavity during nasal surgery could lead to a systemic infectious condition, such as bacteremia, nosocomial infection, or toxic shock syndrome. However, there is no research about the prevalence of nasal carriage in patients with nasal bone fracture.
This was a prospective, double-blind, randomized study about the rate of nasal carriage in 200 patients with nasal bone fracture in Korea. Nasal secretions were taken from both the middle nasal meatus and colonized. All analyses were carried out using SPSS software.
Pathogens were identified in 178 of the 200 cases. Coagulase-negative staphylococci (CNS) were the most cultured bacteria in 127 (66.84%) of the 190 total patients after excluding 10 cases of contaminated samples, and methicillin-resistant coagulase-negative staphylococci (MRCNS) were found in 48 (25.26%). Staphylococcus aureus was the second most identified pathogen, found in 36 (18.95%), followed by 7 cases (3.68%) of methicillin-resistant Staphylococcus aureus (MRSA). The prevalence rate of MRSA in the females was higher than that in the males (RR=4.70; 95% CI, 1.09-20.18), but other demographic factors had no effect on the prevalence rate of MRSA and MRCNS.
The prevalence rate of these pathogens in patients with nasal bone fracture in Korea was similar to other reports. However, few studies have addressed the prevalence rate of CNS and MRCNS in accordance with risk factors or the change in prevalence according to specific prophylaxis against infectious complications. Additional research is needed on the potential connections between clinical factors and microbiological data.
鼻科手术期间鼻腔内的病原体可导致全身性感染，如菌血症、医院感染或中毒性休克综合征。然而，关于鼻骨骨折患者鼻腔带菌情况的研究尚无报道。
这是一项针对韩国200例鼻骨骨折患者鼻腔带菌率的前瞻性、双盲、随机研究。从鼻中道采集鼻分泌物并进行定植。所有分析均使用SPSS软件进行。
200例病例中有178例检出病原体。在排除10例污染样本后的190例患者中，凝固酶阴性葡萄球菌（CNS）是最常培养出的细菌，共127例（66.84%），耐甲氧西林凝固酶阴性葡萄球菌（MRCNS）有48例（25.26%）。金黄色葡萄球菌是第二常见的病原体，有36例（18.95%），耐甲氧西林金黄色葡萄球菌（MRSA）有7例（3.68%）。女性中MRSA的患病率高于男性（RR = 4.70；95% CI，1.09 - 20.18），但其他人口统计学因素对MRSA和MRCNS的患病率没有影响。
韩国鼻骨骨折患者中这些病原体的患病率与其他报道相似。然而，很少有研究根据危险因素探讨CNS和MRCNS的患病率，或针对感染并发症的特定预防措施导致的患病率变化。需要进一步研究临床因素与微生物学数据之间的潜在联系。
