Meikle J, Al-Sarraf A, Li M, Grierson K, Frohlich J
Healthy Heart Program Prevention Clinic, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Clin Med Insights Cardiol. 2013 Sep 15;7:145-51. doi: 10.4137/CMC.S12654. eCollection 2013.
To assess the effects of exercise on resting heart rate (RHR), weight, lipid profile, and blood pressure. We hypothesized that the participants who increased their physical activity would show improvement in their cardiovascular risk factors compared to those who did not.
Retrospective chart review over the mean duration of 4.9 years of follow-up.
Healthy Heart Program Prevention Clinic at St. Paul's Hospital, Vancouver, British Columbia, Canada.
We reviewed 300 charts of patients randomly selected from those who attended the Prevention Clinic between 1984 and 2009. 248 (82.7%) patients were referred for primary prevention and 52 (17.3%) for secondary prevention.
Weight, RHR, lipid profile, and blood pressure were recorded at the initial and last visit.
During a mean of 4.9 years of follow-up, 55% of participants improved their exercise. The mean decrease in the RHR for these patients (group 1) was 5.9 beats per minute (bpm) versus the mean increase of 0.3 bpm for the "no change" group (group 2) (P < 0.01). The mean net weight increase in group 1 was 0.06 kg/year versus 0.25 kg/year in group 2. Because of medications, all patients had a significant improvement in their lipid profiles. Furthermore, there was a statistically significant greater reduction in Framingham Risk Score (FRS) in group 1 versus group 2 (11.8% versus 15.1%, P < 0.01).
Participation in the program significantly reduces modifiable risk factors for cardiovascular disease. Improved exercise regimen results in lower RHR and greater reduction in FRS. However, even in a Prevention Program, despite strong advocacy of the importance of exercise, a significant percentage of participants does not improve their exercise habits.
评估运动对静息心率(RHR)、体重、血脂谱和血压的影响。我们假设,与未增加身体活动的参与者相比,增加身体活动的参与者心血管危险因素会有所改善。
对平均4.9年的随访期进行回顾性病历审查。
加拿大不列颠哥伦比亚省温哥华圣保罗医院的健康心脏计划预防诊所。
我们审查了1984年至2009年间在预防诊所就诊的患者中随机抽取的300份病历。248名(82.7%)患者被转诊进行一级预防,52名(17.3%)患者进行二级预防。
在初次就诊和末次就诊时记录体重、RHR、血脂谱和血压。
在平均4.9年的随访期间,55%的参与者改善了运动情况。这些患者(第1组)的RHR平均下降5.9次/分钟(bpm),而“无变化”组(第2组)平均增加0.3 bpm(P<0.01)。第1组的平均净体重增加为0.06 kg/年,而第2组为0.25 kg/年。由于药物治疗,所有患者的血脂谱都有显著改善。此外,第1组的弗雷明汉风险评分(FRS)较第2组有统计学意义的更大幅度降低(11.8%对15.1%,P<0.01)。
参与该计划可显著降低心血管疾病的可改变危险因素。改善运动方案可降低RHR并更大幅度降低FRS。然而,即使在预防计划中,尽管大力倡导运动的重要性,仍有相当比例的参与者没有改善他们的运动习惯。