Vyas Krishna S, Davenport Daniel L, Ferraris Victor A, Saha Sibu P
From the College of Medicine, and the Department of Surgery, University of Kentucky, Lexington.
South Med J. 2013 Oct;106(10):539-44. doi: 10.1097/SMJ.0000000000000000.
Historically, mediastinoscopy has been the gold standard for the staging of lung cancer. A practice gap exists as the result of a variation in knowledge concerning current trends and practice patterns of mediastinoscopy usage. In addition, there are regional variations in practice-based learning and patient care. Lessons learned during surgeries performed on patients with lung cancer and other advances such as positron emission tomography and endobronchial ultrasound could be universally applied to improve surgeons' management of patient care. The purpose of this study was to assess contemporary practices in the staging of lung cancer.
We queried the Society of Thoracic Surgeons National Database for data regarding mediastinoscopy usage, yield, and variation, both by year and region.
Cases with mediastinoscopy, as a percentage of all cases performed in the database, have significantly decreased from 14.6% in 2006 to 11.4% in 2010 (P < 0.001). The 5-year median rate of mediastinoscopy in lung cancer patients at 163 centers was 15.3% (interquartile range 5.2%-31.7%), indicating significant variation among centers. The overall median center rate also decreased over time from 21.4% (2006) to 10.0% (2010).
With advances in minimally invasive procedures and imaging, mediastinoscopy usage has declined significantly. Our findings are likely to be relevant to both clinical practice and practice guidelines.
从历史上看,纵隔镜检查一直是肺癌分期的金标准。由于对纵隔镜检查当前趋势和应用模式的认识存在差异,导致了实践差距。此外,基于实践的学习和患者护理存在地区差异。在肺癌患者手术过程中吸取的经验教训以及正电子发射断层扫描和支气管内超声等其他进展可普遍应用于改善外科医生对患者护理的管理。本研究的目的是评估肺癌分期的当代实践。
我们查询了胸外科医师协会国家数据库,以获取有关纵隔镜检查使用情况、阳性率和差异的数据,按年份和地区进行分类。
纵隔镜检查病例占数据库中所有病例的百分比已从2006年的14.6%显著下降至2010年的11.4%(P<0.001)。163个中心肺癌患者纵隔镜检查的5年中位率为15.3%(四分位间距5.2%-31.7%),表明各中心之间存在显著差异。总体中心中位率也随时间从2006年的21.4%降至2010年的10.0%。
随着微创程序和成像技术的进步,纵隔镜检查的使用显著下降。我们的研究结果可能与临床实践和实践指南都相关。