FertileSafe, Shlomzion Hamalca 59/5, Tel Aviv, 62266, Israel,
Adv Exp Med Biol. 2013;761:69-83. doi: 10.1007/978-1-4614-8214-7_6.
Vitrification is a physical process by which a liquid is transformed into a solid of amorphous glass form. It was only at the end of the nineteenth century (1898) that Gustav Heinrich Johann Apollon Tammann pointed out that a large number of substances can be obtained as glasses and suggested that this property might be universal (Tammann, Zeitschrift for Physikalische Chemie; 25: 441-479, 1898). Basically, vitrification is the supercooling of a liquid to a temperature at which the viscosity is so high that it can be defined as being at a solid state. The understanding of the vitrification process has been deepened over the years and has been applied for cryopreservation and currently is the method of choice for preserving oocytes and embryos.
玻璃化是一种将液体转变为无定形玻璃态固体的物理过程。直到 19 世纪末(1898 年),古斯塔夫·海因里希·约翰·阿普尔顿·坦曼才指出,大量物质可以被制成玻璃,并提出这种特性可能具有普遍性(坦曼,《物理化学杂志》;25:441-479,1898 年)。基本上,玻璃化是将液体冷却到粘度如此之高的温度,以至于可以定义为处于固态。多年来,人们对玻璃化过程的理解不断加深,并将其应用于冷冻保存,目前是保存卵母细胞和胚胎的首选方法。