Mageed Mahmoud, Berner Dagmar, Jülke Henriette, Hohaus Christian, Brehm Walter, Gerlach Kerstin
Large Animal Clinic for Surgery, Faculty of Veterinary Medicine, University of Leipzig, Leipzig, Germany. ; Department of Surgery and Anaesthesia, Faculty of Veterinary Medicine, University of Khartoum, Shambat, Sudan.
Lab Anim Res. 2013 Sep;29(3):138-47. doi: 10.5625/lar.2013.29.3.138. Epub 2013 Sep 27.
The sheep spine is widely used as a model for preclinical research in human medicine to test new spinal implants and surgical procedures. Therefore, precise morphometric data are needed. The present study aimed to provide computed tomographic (CT) morphometry of sheep thoracolumbar spine. Five adult normal Merino sheep were included in this study. Sheep were anaesthetised and positioned in sternal recumbency. Subsequently, transverse and sagittal images were obtained using a multi-detector-row helical CT scanner. Measurements of the vertebral bodies, pedicles, intervertebral disc and transverse processes were performed with dedicated software. Vertebral bodies and the spinal canal were wider than they were deep, most obviously in the lumbar vertebrae. The intervertebral discs were as much as 57.4% thicker in the lumbar than in the thoracic spine. The pedicles were higher and longer than they were wide over the entire thoracolumbar spine. In conclusion, the generated data can serve as a CT reference for the ovine thoracolumbar spine and may be helpful in using sheep spine as a model for human spinal research.
绵羊脊柱被广泛用作人类医学临床前研究的模型，以测试新型脊柱植入物和手术程序。因此，需要精确的形态测量数据。本研究旨在提供绵羊胸腰椎的计算机断层扫描（CT）形态测量数据。本研究纳入了五只成年正常美利奴绵羊。绵羊被麻醉并置于仰卧位。随后，使用多排螺旋CT扫描仪获取横断位和矢状位图像。使用专用软件对椎体、椎弓根、椎间盘和横突进行测量。椎体和椎管的宽度大于深度，在腰椎最为明显。腰椎间盘比胸椎间盘厚达57.4%。在整个胸腰椎，椎弓根的高度和长度大于宽度。总之，所生成的数据可作为绵羊胸腰椎的CT参考，可能有助于将绵羊脊柱用作人类脊柱研究的模型。
