Roels Josephine, Hassoun Roy, Massenzio M, Ronel S, Lafon Y, Viguier Eric, Cachon Thibaut
Department of Small Animal Surgery, VetAgro-Sup, Campus Vétérinaire de Lyon, 69280 Marcy L'Etoile, France.
Université de Lyon, VetAgro Sup, UPSP 2016 A104, Unité ICE, Marcy l'Etoile, France.
Vet Anim Sci. 2022 Jan 17;15:100233. doi: 10.1016/j.vas.2022.100233. eCollection 2022 Mar.
The goat spine is widely used as an animal model for preclinical research in human medicine to test new spinal implants and surgical procedures. Therefore, precise morphometric data are needed. This study aims to provide morphometric data of the goat thoracolumbar vertebrae and to define the parameters/characteristics of the optimum implantation corridors for pedicle screws in the thoracolumbar spine in goat. Eleven 36-month-old adult alpine goats were included in this study, and a sample of 198 vertebrae was measured. Subsequently, transverse and sagittal images were obtained using a multi-detector-row helical computed tomography (CT) scanner. Measurements of the vertebral bodies (ventral body width VBW, ventral body depth VBD, ventral body height ventral VBHv, ventral body high dorsal VBHd, spinal canal depth SCD, spinal canal width SCW), pedicles (pedicle length PDL, pedicle width PDW, pedicle angle PA and pedicle axis length PAL), intervertebral disc (DT) and transverse process length (TPL) were performed with dedicated software. The vertebral bodies and the spinal canal were wider than deep, mostly evident in the lumbar region. The intervertebral discs were as much as 65.7% thicker in the lumbar spine than in the thoracic spine. The pedicles were longer than wide over the thoracic and lumbar spines. The insertion angles in pedicle were approximately 30° for the T2-T4 segment, 25° for the T5-T6 segment, 23° for the T6 to T11 segment, 20° for T11 to L3, 25° for L4 and 30° for L5 and L6. In conclusion, the generated data can serve as a CT reference for the caprine thoracolumbar spine and may be helpful in using the goat spine as an animal model for human spinal research.
山羊脊柱被广泛用作人类医学临床前研究的动物模型，以测试新型脊柱植入物和手术程序。因此，需要精确的形态测量数据。本研究旨在提供山羊胸腰椎的形态测量数据，并确定山羊胸腰椎椎弓根螺钉最佳植入通道的参数/特征。本研究纳入了11只36月龄的成年高山山羊，并对198个椎骨样本进行了测量。随后，使用多排螺旋计算机断层扫描（CT）扫描仪获取横断位和矢状位图像。使用专用软件对椎体（椎体腹侧宽度VBW、椎体腹侧深度VBD、椎体腹侧高度VBHv、椎体背侧高度VBHd、椎管深度SCD、椎管宽度SCW）、椎弓根（椎弓根长度PDL、椎弓根宽度PDW、椎弓根角度PA和椎弓根轴长PAL）、椎间盘（DT）和横突长度（TPL）进行测量。椎体和椎管宽度大于深度，在腰椎区域最为明显。腰椎间盘比胸椎间盘厚65.7%。胸腰椎的椎弓根长度大于宽度。T2-T4节段椎弓根的插入角度约为30°，T5-T6节段为25°，T6至T11节段为23°，T11至L3节段为20°，L4节段为25°，L5和L6节段为30°。总之，所生成的数据可作为山羊胸腰椎的CT参考，可能有助于将山羊脊柱用作人类脊柱研究的动物模型。
