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一般人群调查血样中选定持久性卤代烃的残留及代谢物

Residues and metabolites of selected persistent halogenated hydrocarbons in blood specimens from a general population survey.

作者信息

Murphy R, Harvey C

出版信息

Environ Health Perspect. 1985 May;60:115-20. doi: 10.1289/ehp.8560115.

DOI:10.1289/ehp.8560115
PMID:2411534
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1568559/
Abstract

The National Center for Health Statistics collaborated with the National Human Monitoring Program of the U.S. Environmental Protection Agency (EPA) in a four-year study to assess the exposure of the general population to selected pesticides through analysis of blood serum and urine specimens. Specimens were collected on a national probability half-sample of persons 12-74 years of age from 64 locations across the United States comprising the sample areas in the Second National Health and Examination Survey (NHANES II) and analyzed for selected organochlorine, carbamate, chlorophenoxy and organophosphorus pesticides. Medical, nutritional and pesticide usage data are also available for each sample person. Results of the blood serum analyses indicate that the general population is being exposed to some of these types of pesticides. For selected pesticide residues, the percent quantifiable positives and median serum levels by age group are presented for three regions of the United States. Since 1970, EPA has conducted a national probability sampling of human adipose tissue. Specimens obtained on a survey design representative of the general population were analyzed for selected organochlorine pesticides and toxic chemicals. Findings from the 1979 survey also indicate exposure of the general population to some of these chemicals.

摘要

美国国家卫生统计中心与美国环境保护局(EPA)的国家人体监测项目合作,开展了一项为期四年的研究,通过分析血清和尿液样本,评估普通人群对特定农药的接触情况。样本取自美国64个地点12至74岁人群的全国概率半样本,这些地点构成了第二次全国健康和检查调查(NHANES II)的样本区域,并对选定的有机氯、氨基甲酸酯、氯苯氧基和有机磷农药进行了分析。每个样本人员的医疗、营养和农药使用数据也可获取。血清分析结果表明,普通人群正在接触其中一些类型的农药。针对选定的农药残留,列出了美国三个地区按年龄组划分的可定量阳性百分比和血清中位数水平。自1970年以来,EPA对人体脂肪组织进行了全国概率抽样。对按照代表普通人群的调查设计获取的样本,分析了选定的有机氯农药和有毒化学品。1979年调查的结果也表明普通人群接触到了其中一些化学品。