Murphy R S, Kutz F W, Strassman S C
Environ Health Perspect. 1983 Feb;48:81-6. doi: 10.1289/ehp.834881.
The National Center for Health Statistics collaborated with the National Human Monitoring Program of the U.S. Environmental Protection Agency (EPA) in a four-year study to assess the exposure of the general population to selected pesticides through analysis of blood serum and urine specimens. Specimens were collected on a national probability half sample of persons 12-74 years of age from 64 locations across the United States comprising the sample areas in the Second Health and Nutrition Examination Survey (NHANES II) and analyzed for selected organochlorine, carbamate, chlorophenoxy and organophosphorus pesticides. Medical, nutritional and pesticide usage data are also available for each sample person. Preliminary results of the blood serum and urine analyses indicate that the general population is being exposed to some of these types of pesticides. Since 1970, EPA has conducted a national probability sampling of human adipose tissue. Specimens obtained on a survey design representative of the general population were analyzed for selected organochlorine pesticides and toxic chemicals. Findings from the 1978 survey also indicate exposure of the general population to some of these chemicals. Medical data collected from both surveys have yielded no overt correlations between health effects and residue levels. More intensive statistical analyses are underway to investigate the possible existence of more subtle relationships.
美国国家卫生统计中心与美国环境保护局（EPA）的国家人体监测计划合作，开展了一项为期四年的研究，通过分析血清和尿液样本，评估普通人群对特定农药的接触情况。样本是从美国64个地点抽取的12至74岁人群的全国概率半样本，这些地点构成了第二次健康与营养检查调查（NHANES II）的样本区域，并对选定的有机氯、氨基甲酸酯、氯苯氧基和有机磷农药进行了分析。每个样本人员还提供了医疗、营养和农药使用数据。血清和尿液分析的初步结果表明，普通人群正在接触其中一些类型的农药。自1970年以来，EPA对人体脂肪组织进行了全国概率抽样。对按照代表普通人群的调查设计获取的样本，分析了选定的有机氯农药和有毒化学品。1978年调查的结果也表明普通人群接触到了其中一些化学品。从两项调查中收集的医疗数据未显示健康影响与残留水平之间存在明显关联。正在进行更深入的统计分析，以调查是否可能存在更细微的关系。
