Center for Cell-Encapsulation Research, Department of Chemistry, KAIST, Daejeon 305-701 (Korea).
Angew Chem Int Ed Engl. 2013 Nov 18;52(47):12279-82. doi: 10.1002/anie.201305081. Epub 2013 Oct 2.
Hard-shell case: Using a (RKK)4 D8 peptide allows mineralization to occur under cytocompatible conditions. Thus individual Chlorella cells could be encapsulated within a SiO2 -TiO2 nanoshell with high cell viability (87 %). The encapsulated Chlorella showed an almost threefold increase in their thermo-tolerance after 2 h at 45 °C.
使用(RKK)4 D8 肽可在细胞相容条件下实现矿化。因此,单个小球藻细胞可以被包裹在具有高细胞活力(87%)的 SiO2 -TiO2 纳米壳内。在 45°C 下 2 小时后,被包裹的小球藻的耐热性几乎提高了三倍。