Department of Human and Engineered Environmental Studies, Graduate School of Frontier Sciences, University of Tokyo , Kashiwa, Japan.
J Sports Sci Med. 2010 Jun 1;9(2):224-30. eCollection 2010.
The purpose of this study was to examine the metabolic and cardiovascular response to exercise without (CON) or with (BFR) restricted blood flow to the muscles. Ten young men performed upright cycle exercise at 20, 40, and 60% of maximal oxygen uptake, VO2max in both conditions while metabolic and cardiovascular parameters were determined. Pre-exercise VO2 was not different between CON and BFR. Cardiac output (Q) was similar between the two conditions as a 25% reduction in stroke volume (SV) observed in BFR was associated with a 23% higher heart rate (HR) in BFR compared to CON. As a result rate-pressure product (RPP) was higher in the BFR but there was no difference in mean arterial pressure (MAP) or total peripheral resistance (TPR). During exercise, VO2 tended to increase with BFR (~10%) at each workload. Q increased in proportion to exercise intensity and there were no differences between conditions. The increase in SV with exercise was impaired during BFR; being ~20% lower in BFR at each workload. Both HR and RPP were significantly greater at each workload with BFR. MAP and TPR were greater with BFR at 40 and 60% VO2max. In conclusion, the BFR employed impairs exercise SV but central cardiovascular function is maintained by an increased HR. BFR appears to result in a greater energy demand during continuous exercise between 20 and 60% of control VO2max; probably indicated by a higher energy supply and RPP. When incorporating BFR, HR and RPP may not be valid or reliable indicators of exercise intensity. Key pointsBlood flow reduction (BFR) employed impairs stroke volume (SV) during exercise, but central cardiovascular function is maintained by an increased heart rate (HR).BFR appears to result in a greater energy demand during continuous exercise between 20 and 60% of control VO2max;Probably indicated by a higher energy supply (VO2) and rate-pressure product (HR x systolic blood pressure).
本研究旨在探讨在不（CON）或限制肌肉血流（BFR）的情况下运动时的代谢和心血管反应。10 名年轻男性在两种情况下以 20%、40%和 60%最大摄氧量（VO2max）的直立式自行车运动，同时测定代谢和心血管参数。CON 和 BFR 之间的运动前 VO2 没有差异。心输出量（Q）在两种情况下相似，因为 BFR 中观察到的每搏量（SV）减少 25%，与 CON 相比，BFR 中的心率（HR）增加了 23%。因此，BFR 中的心率乘积（RPP）更高，但平均动脉压（MAP）或总外周阻力（TPR）没有差异。在运动过程中，BFR 时 VO2 趋于以 10%的比例增加。Q 与运动强度成比例增加，两种情况下没有差异。SV 在 BFR 期间随运动而增加受到损害；在 BFR 中，每个工作量的 SV 降低约 20%。在 BFR 中，HR 和 RPP 在每个工作量时都明显更大。在 40%和 60%的 VO2max 时，MAP 和 TPR 随 BFR 增加。总之，BFR 会损害运动时的 SV，但通过增加 HR 来维持中心心血管功能。BFR 似乎在连续运动中 20%至 60%的对照 VO2max 之间产生更大的能量需求；可能通过更高的能量供应和 RPP 来表示。在包含 BFR 时，HR 和 RPP 可能不是运动强度的有效或可靠指标。关键点血流减少（BFR）在运动期间损害了每搏量（SV），但通过增加心率（HR）来维持中心心血管功能。BFR 似乎在连续运动中 20%至 60%的对照 VO2max 之间产生更大的能量需求；可能通过更高的能量供应（VO2）和心率乘积（HR×收缩压）来表示。
