Department of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Chicago, Illinois 60607 (USA), Fax: (+1) 312-355-0836 http://www.chem.uic.edu/vggroup/
Chemistry. 2013 Nov 18;19(47):15836-40. doi: 10.1002/chem.201303511. Epub 2013 Oct 21.
for remote aromatic C–H oxygenation reaction have been developed. Method 1, the Cu-catalyzed oxygenation reaction is highly efficient for cyclization of electron-neutral and electron-rich biaryl carboxylic acids into 3,4-benzocoumarins. Method 2, the KSO-mediated oxygenation reaction, is more general and practical for cyclization of substrates with electron- donating and -withdrawing groups (see scheme).
已开发出用于远程芳族 C–H 氧化反应的方法。方法 1，Cu 催化的氧化反应对于电子中性和富电子联苯羧酸环化成 3,4-苯并香豆素非常有效。方法 2，KSO 介导的氧化反应对于具有供电子和吸电子基团的底物的环化更为通用和实用（见方案）。
