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头颈部癌症患者治疗前后的营养与免疫调查。

Nutritional and immunological investigations in head and neck cancer patients before and after therapy.

作者信息

Picker H, Bichler E

出版信息

Arch Otorhinolaryngol. 1985;242(2):149-53. doi: 10.1007/BF00454414.

DOI:10.1007/BF00454414
PMID:2415099
Abstract

We studied the nutritional and immunological states of 20 patients with advanced head and neck carcinomas. Treatment included chemotherapy with methotrexate, cis-platinum and bleomycin prior to operation and radiotherapy. Nutritional and immunological parameters were examined before and after each therapy given. Most of these parameters decreased during chemotherapy. However, while we found that nutrition improved or normalized by the end of the primary tumor treatment, immunologic parameters failed to change significantly.

摘要

我们研究了20例晚期头颈癌患者的营养和免疫状态。治疗包括术前使用甲氨蝶呤、顺铂和博来霉素进行化疗以及放疗。在每次给予治疗前后检测营养和免疫参数。这些参数中的大多数在化疗期间下降。然而，我们发现，在原发性肿瘤治疗结束时营养状况得到改善或恢复正常，而免疫参数却没有明显变化。

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Nutritional and immunological investigations in head and neck cancer patients before and after therapy.头颈部癌症患者治疗前后的营养与免疫调查。
Arch Otorhinolaryngol. 1985;242(2):149-53. doi: 10.1007/BF00454414.
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HNO. 1980 Dec;28(12):405-8.
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[Chemotherapy of advanced head and neck cancer with a combination of bleomycin, vincristine, methotrexate and hydroxyuree or cis-dichloro-diamino-platinium. Analysis of local and general parameters of prognosis (author's transl)].
Bull Cancer. 1980;67(3):269-80.
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Phase-II study of cis-diammine-dichloro platinum (cis-platinum), bleomycin and methotrexate for advanced squamous cell carcinoma of head and neck.顺二氨二氯铂（顺铂）、博来霉素和甲氨蝶呤用于晚期头颈部鳞状细胞癌的II期研究。
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Combination chemotherapy with cisplatin, bleomycin, and methotrexate in patients with advanced head and neck cancer.顺铂、博来霉素和甲氨蝶呤联合化疗用于晚期头颈癌患者。
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[Randomized trial of vincristin-methotrexate-bleomycin and cis-platin or detorubicin for advanced head and neck cancer (author's transl)].长春新碱-甲氨蝶呤-博来霉素与顺铂或多柔比星治疗晚期头颈癌的随机试验（作者译）
Bull Cancer. 1981;68(5):422-7.

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本文引用的文献

1
Prediction of survival in head and neck cancer based on leukocyte sedimentation in Ficoll-Hypaque gradients.基于菲可-泛影葡胺梯度中白细胞沉降对头颈癌患者生存情况的预测
Laryngoscope. 1980 Aug;90(8 Pt 1):1281-90.
2
Recent theoretical and practical problems in the cell mediated immunological reactions in cases of laryngeal cancer.喉癌病例中细胞介导免疫反应的近期理论与实践问题
Acta Otolaryngol. 1980 Mar-Apr;89(3-4):195-201. doi: 10.3109/00016488009127128.
3
[Investigations of unspecific immune reactivity in patients with head and neck carcinoma (author's transl)].
头颈部癌患者非特异性免疫反应的研究（作者译）
Arch Otorhinolaryngol. 1981;232(2):145-63. doi: 10.1007/BF00505034.
4
Plasma levels of retinol and retinol-binding protein in patients with squamous cell carcinomas of the head and neck region.头颈部鳞状细胞癌患者的血浆视黄醇和视黄醇结合蛋白水平。
Arch Otorhinolaryngol. 1982;236(2):115-21. doi: 10.1007/BF00454030.
5
The effect of chemotherapy in relation to pathohistological tumour grading in head and neck cancer.化疗对头颈部癌病理组织学肿瘤分级的影响。
Arch Otorhinolaryngol. 1983;238(3):197-204. doi: 10.1007/BF00453929.
6
Three-year results of combined modality therapy in locally advanced, resectable squamous cell carcinoma of the head and neck.局部晚期可切除头颈部鳞状细胞癌综合治疗的三年结果
Acta Otolaryngol. 1985 Jul-Aug;100(1-2):134-9. doi: 10.3109/00016488509108598.
7
T-cell rosette test in squamous cell carcinoma of the head and neck.头颈部鳞状细胞癌的T细胞玫瑰花结试验
Arch Otolaryngol. 1976 Mar;102(3):171-5. doi: 10.1001/archotol.1976.00780080093013.
8
Dinitrochlorobenzene skin sensitization and peripheral lymphocyte count: predictors of survival in head and neck cancer.二硝基氯苯皮肤致敏作用与外周淋巴细胞计数：头颈部癌症生存的预测指标
Ann Otol Rhinol Laryngol. 1976 Jul-Aug;85(4 Pt 1):517-22. doi: 10.1177/000348947608500413.
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DiGeorge syndrome associated with multiple squamous cell carcinomas.
Arch Otolaryngol. 1977 Feb;103(2):105-7. doi: 10.1001/archotol.1977.00780190085011.
10
Cellular immunity in patients with laryngeal cancer developing additional primary malignant tumors.喉癌患者发生额外原发性恶性肿瘤时的细胞免疫
Ann Otol Rhinol Laryngol. 1979 May-Jun;88(3 Pt 1):311-5. doi: 10.1177/000348947908800302.