Premalatha B R, Patil Shankargouda, Rao Roopa S, Reddy Narendranatha P, Indu M
Department of Oral Pathology, M S Ramaiah Dental College Bangalore, India.
J Int Oral Health. 2013 Apr;5(2):59-69.
The practice of pathology is currently undergoing significant change, due to advances in the field of molecular pathology. Tumor markers are molecules that help the pathologists for confirmatory diagnosis of histopathologically confounding lesions. Odontogenic tumors are relatively rare with estimated incidence of less than 0.5 cases/ 100,000 population per year. Odontogenic tumors can pose diagnostic challenges because of overlapping histology. But, appropriate diagnosis is crucial as their treatment modality and prognosis differ; in these situations tumor markers can be helpful. But lack of comprehensive literature on specific markers for odontogenic tumors imposes pathologists to think aimlessly about various markers to arrive at an appropriate diagnosis. With this background, it is our attempt at compiling diagnostically important odontogenic tumor markers. Also, a note is added on tumor behaviour studies in common clinically important odontogenic tumors: Ameloblastoma and Keratocystic odontogenic tumor.
Tumor markers, Odontogenic tumors, Ameloblastoma, Keratocystic odontogenic tumor HOW TO CITE THIS ARTICLE: Premalatha B R, Patil S, Rao R S, Reddy N P, Indu M. Odontogenic Tumor Markers - An Overview. J Int Oral Health 2013; 5(2):65-75. How to cite this article: Premalatha B R, Patil S, Rao R S, Reddy N P, Indu M. Odontogenic Tumor Markers - An Overview. J Int Oral Health 2013; 5(2):65-75.
由于分子病理学领域的进展，病理学实践目前正在经历重大变革。肿瘤标志物是有助于病理学家对组织病理学上混淆不清的病变进行确诊的分子。牙源性肿瘤相对罕见，估计每年发病率低于每10万人0.5例。由于组织学重叠，牙源性肿瘤可能带来诊断挑战。但是，由于其治疗方式和预后不同，正确诊断至关重要；在这些情况下，肿瘤标志物可能会有所帮助。但是，缺乏关于牙源性肿瘤特定标志物的全面文献，使得病理学家在思考各种标志物以做出正确诊断时毫无头绪。在此背景下，我们试图汇编具有诊断重要性的牙源性肿瘤标志物。此外，还添加了关于常见临床重要牙源性肿瘤（成釉细胞瘤和牙源性角化囊性瘤）肿瘤行为研究的说明。
肿瘤标志物；牙源性肿瘤；成釉细胞瘤；牙源性角化囊性瘤
Premalatha B R, Patil S, Rao R S, Reddy N P, Indu M. 牙源性肿瘤标志物——概述。《国际口腔健康杂志》2013年；5(2):65 - 75。如何引用本文：Premalatha B R, Patil S, Rao R S, Reddy N P, Indu M. 牙源性肿瘤标志物——概述。《国际口腔健康杂志》2013年；5(2):65 - 75。
