Rastogi Varun, Chaurasia Sandhya, Maddheshiya Nisha, Dhungel Dilasha
Department of Oral & Maxillofacial Pathology, Universal College of Medical Sciences, Bhairahawa, Nepal.
Institute of Medical Sciences, BHU, Varanasi, India.
Discov Oncol. 2024 Oct 15;15(1):558. doi: 10.1007/s12672-024-01237-0.
Odontogenic tumors are a group of tumors that originate from the tissues associated with tooth development and are classified into benign or malignant based on their behavior and characteristics. Tumor markers are substances that can be found in the blood, urine, or tissues of individuals with cancer. They are the substances produced either by tumor cells itself or by the body in response to tumor growth, can sometimes be used in the diagnosis, prognosis, and monitoring of various types of tumors. However, the use of tumor markers in odontogenic tumors is not as common as it is in other types of cancers, and their utility in this context is limited. Tumor markers are not the main tools for diagnosing cancer; instead, they serve as supplementary laboratory tests to aid in the diagnosis. Researchers continue to investigate potential biomarkers to improve our understanding of these tumors and their behavior. With this concept in mind, the objective of this study is to elucidate the key diagnostic markers essential for diagnosing odontogenic tumors.
牙源性肿瘤是一组起源于与牙齿发育相关组织的肿瘤,根据其行为和特征分为良性或恶性。肿瘤标志物是在癌症患者的血液、尿液或组织中可以检测到的物质。它们是由肿瘤细胞自身产生或机体对肿瘤生长做出反应而产生的物质,有时可用于各种类型肿瘤的诊断、预后评估和监测。然而,肿瘤标志物在牙源性肿瘤中的应用不如在其他类型癌症中普遍,其在这种情况下的效用有限。肿瘤标志物不是诊断癌症的主要工具;相反,它们作为辅助实验室检测手段来协助诊断。研究人员继续探索潜在的生物标志物,以增进我们对这些肿瘤及其行为的了解。基于这一理念,本研究的目的是阐明诊断牙源性肿瘤必不可少的关键诊断标志物。