Department of Psychology, University of California, Davis, CA 95616, United States.
Department of Psychology, University of California, Davis, CA 95616, United States; Center for Neuroscience, University of California, Davis, CA 95616, United States.
Neuropsychologia. 2014 Jan;52:19-26. doi: 10.1016/j.neuropsychologia.2013.10.006. Epub 2013 Oct 21.
Although it is well established that regions in the medial temporal lobes are critical for explicit memory, recent work has suggested that one medial temporal lobe subregion--the perirhinal cortex (PRC)--may also support conceptual priming, a form of implicit memory. Here, we sought to investigate whether activity reductions in PRC, previously linked to familiarity-based recognition, might also support conceptual implicit memory retrieval. Using a free association priming task, the current study tested the prediction that PRC indexes conceptual priming independent of contributions from perceptual and response repetition. Participants first completed an incidental semantic encoding task outside of the MRI scanner. Next, they were scanned during performance of a free association priming task, followed by a recognition memory test. Results indicated successful conceptual priming was associated with decreased PRC activity, and that an overlapping region within the PRC also exhibited activity reductions that covaried with familiarity during the recognition memory test. Our results demonstrate that the PRC contributes to both conceptual priming and familiarity-based recognition, which may reflect a common role of this region in implicit and explicit memory retrieval.
虽然内侧颞叶区域对显式记忆至关重要已得到充分证实，但最近的研究表明，内侧颞叶的一个亚区——旁海马回（PRC）——也可能支持概念启动，这是一种内隐记忆。在这里，我们试图研究先前与基于熟悉度的识别相关的 PRC 活动减少是否也支持概念性内隐记忆检索。使用自由联想启动任务，本研究预测 PRC 会在不考虑感知和反应重复贡献的情况下对内隐记忆检索进行索引。参与者首先在 MRI 扫描仪外完成一项偶然的语义编码任务。接下来，他们在执行自由联想启动任务时进行扫描，然后进行识别记忆测试。结果表明，成功的概念启动与 PRC 活动减少有关，而 PRC 内的一个重叠区域在识别记忆测试中也表现出与熟悉度相关的活动减少。我们的结果表明，PRC 既参与了概念启动，也参与了基于熟悉度的识别，这可能反映了该区域在隐式和显式记忆检索中的共同作用。
