Rosario Michael, McMahon Kevin, Finelli Pasquale F
Department of Neurology, University of Connecticut, Hartford Hospital, Hartford, Connecticut, CT, USA.
Neurohospitalist. 2013 Jul;3(3):125-30. doi: 10.1177/1941874412467806.
Magnetic resonance imaging (MRI) findings associated with chronic liver disease are characterized by cerebral atrophy and bilateral, symmetric hyperintensities of the globus pallidus on T1-weighted images without corresponding signal intensities in T2-weighted images. Recently, distinct MRI changes of acute hepatic encephalopathy have been described which may be misinterpreted given their resemblance to hypoxic-ischemic injury imaging changes as well as their limited description in the neurologic literature. We describe 3 cases of acute hyperammonemic encephalopathy primarily characterized by restricted diffusion involving the insular and cingulate cortices and thalamus bilaterally.
与慢性肝病相关的磁共振成像（MRI）表现的特征为脑萎缩以及在T1加权图像上苍白球呈双侧对称性高信号，而在T2加权图像上无相应信号强度改变。最近，已有关于急性肝性脑病独特MRI变化的描述，但鉴于其与缺氧缺血性损伤成像变化相似，且在神经学文献中的描述有限，这些变化可能会被误解。我们描述了3例急性高氨血症性脑病，其主要特征为双侧岛叶、扣带回皮质及丘脑出现扩散受限。
