State Key Laboratory of Analytical Chemistry for Life Science and Institute of Chemical Biology and Drug Innovation, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing 210093, China.
Org Lett. 2013 Nov 1;15(21):5520-3. doi: 10.1021/ol4026827. Epub 2013 Oct 15.
A mechanistically new strategy has been described for the simple, practical, and environmentally friendly preparation of 6-(trifluoromethyl)phenanthridine derivatives using ionic isocyanide insertion from biphenyl isocyanide derivatives and Umemoto's reagent. These reactions were promoted only by inorganic base in good-to-excellent chemical yields without any external stoichiometric oxidants and radical initiators.
一种新的机械策略被描述用于简单、实用和环保的制备 6-(三氟甲基)菲啶衍生物，使用离子异氰化物插入从联苯异氰化物衍生物和 Umemoto 的试剂。这些反应仅在无机碱的促进下进行，具有良好到优秀的化学产率，无需任何外部化学计量氧化剂和自由基引发剂。
