Department of Ophthalmology, Seoul National University College of Medicine, 101 Daehak-ro, Chongno-gu, Seoul, 110-744, Republic of Korea.
Jpn J Ophthalmol. 2014 Jan;58(1):40-6. doi: 10.1007/s10384-013-0287-z. Epub 2013 Nov 6.
To investigate the association between the trends in the rates of laser peripheral iridotomy (LPI) for primary angle closure (PAC) or primary angle-closure glaucoma (PACG) and cataract surgery in Korea.
Acute or subacute PAC(G) patients (251,769) along with patients who had undergone LPI (20,632) or cataract surgery (1,163,729) between 2007 and 2012 were included. The LPI rate was defined as the number of LPI cases per 100 PAC(G) patients by quarter; the cataract surgery rate was defined as the number of cataract surgeries per 100,000 population by quarter.
The number of acute or subacute PAC(G) patients per 100,000 population showed a gradual increase, specifically from 45.63 in the first quarter of 2007 to 49.56 in the second quarter of 2012. The LPI rate manifested a slow decline, from 9.59 to 7.94, and the cataract surgery rate showed a sharp rise, from 260.75 to 387.53, over the same period. In other words, a negative correlation tendency between the two rate trends (r = -0.244, P = 0.273) was revealed. With respect to age, significant negative correlations were observed in the 40-49 (r = -0.488, P = 0.021) and ≥ 70 (r = -0.450, P = 0.036) groups.
The respective trends in the LPI and cataract surgery rates showed a negative correlation. Although other possible explanations might exist, this result supports the hypothesis that cataract surgery contributes to a reduction in the incidence of LPI in PAC(G) patients.
调查韩国激光周边虹膜切开术（LPI）治疗原发性闭角型（PAC）或原发性闭角型青光眼（PACG）的趋势与白内障手术之间的关联。
纳入 2007 年至 2012 年间急性或亚急性 PAC(G)患者（251769 例）以及行 LPI（20632 例）或白内障手术（1163729 例）的患者。LPI 率定义为每 100 例 PAC(G)患者的 LPI 例数；白内障手术率定义为每 10 万人的白内障手术例数。
每 10 万人急性或亚急性 PAC(G)患者的数量呈逐渐增加趋势，具体从 2007 年第一季度的 45.63 例增加到 2012 年第二季度的 49.56 例。LPI 率呈缓慢下降趋势，从 9.59 降至 7.94，同期白内障手术率呈急剧上升趋势，从 260.75 例增至 387.53 例。换句话说，这两个比率趋势之间存在负相关趋势（r=-0.244，P=0.273）。就年龄而言，在 40-49 岁（r=-0.488，P=0.021）和≥70 岁（r=-0.450，P=0.036）组中观察到显著的负相关关系。
LPI 和白内障手术率的趋势呈负相关。尽管可能存在其他解释，但这一结果支持了白内障手术有助于降低 PAC(G)患者 LPI 发生率的假说。
