Kiviniemi H, Laitinen S, Ståhlberg M, Larmi M, Kairaluoma M
Acta Chir Scand. 1986 Jan;152:43-7.
The effect of thyrotropin-releasing hormone (TRH) in continuous infusion (a bolus of 400 micrograms followed by 200 micrograms/hour for 6 hours) was studied in 35 patients (17 TRH, 18 placebo) with acute pancreatitis in a double-blind investigation. Three hours after the start of infusion, significantly more patients were pain-free in the TRH group than in the placebo group, but not thereafter. TRH also significantly reduced the serum amylase and lipase levels, but did not influence the clinical course of pancreatitis.
在一项双盲研究中，对35例急性胰腺炎患者（17例使用促甲状腺激素释放激素（TRH），18例使用安慰剂）进行了持续输注TRH（先推注400微克，随后以200微克/小时的速度输注6小时）效果的研究。输注开始3小时后，TRH组无痛的患者明显多于安慰剂组，但此后并非如此。TRH还显著降低了血清淀粉酶和脂肪酶水平，但并未影响胰腺炎的临床病程。
