Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere FIN-33521, Finland.
Nutrients. 2013 Nov 6;5(11):4380-9. doi: 10.3390/nu5114380.
Many celiac disease patients tolerate oats, but limited data are available on its long-term consumption. This was evaluated in the present study, focusing on small-bowel mucosal histology and gastrointestinal symptoms in celiac adults maintaining a strict gluten-free diet with or without oats. Altogether 106 long-term treated celiac adults were enrolled for this cross-sectional follow-up study. Daily consumption of oats and fiber was assessed, and small-bowel mucosal morphology and densities of CD3+, αβ+ and γσ+ intraepithelial lymphocytes determined. Gastrointestinal symptoms were assessed by a validated Gastrointestinal Symptom Rating Scale questionnaire. Seventy (66%) out of the 106 treated celiac disease patients had consumed a median of 20 g of oats (range 1-100 g) per day for up to eight years; all consumed oat products bought from general stores. Daily intake and long-term consumption of oats did not result in small-bowel mucosal villous damage, inflammation, or gastrointestinal symptoms. Oat-consumers had a significantly higher daily intake of fiber than those who did not use oats. Two thirds of celiac disease patients preferred to use oats in their daily diet. Even long-term ingestion of oats had no harmful effects.
许多乳糜泻患者可以耐受燕麦，但关于其长期食用的数据有限。本研究评估了乳糜泻成年人在严格无麸质饮食中是否添加燕麦及其对小肠黏膜组织学和胃肠道症状的影响。共有 106 名长期接受治疗的乳糜泻成年人参与了这项横断面随访研究。评估了燕麦和纤维的每日摄入量，并确定了小肠黏膜形态和 CD3+、αβ+和 γσ+上皮内淋巴细胞的密度。通过经过验证的胃肠道症状评分量表问卷评估胃肠道症状。在 106 名接受治疗的乳糜泻患者中，有 70 名（66%）患者每天中位数摄入 20 克燕麦（范围为 1-100 克），长达 8 年；所有患者均食用从杂货店购买的燕麦制品。燕麦的每日摄入量和长期食用不会导致小肠黏膜绒毛损伤、炎症或胃肠道症状。与不食用燕麦的患者相比，燕麦食用者的膳食纤维每日摄入量明显更高。三分之二的乳糜泻患者更喜欢在日常饮食中使用燕麦。即使长期摄入燕麦也没有不良影响。
